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Recombinant Human S100A6, His-tagged

Cat.No. : S100A6-916H
Product Overview : Recombinant Human S100A6 encoding the human mature S100A6 (Met1-Gly90) with 6 His tag on the N-Terminus was expressed inE. Coli. This protein was purified by Ni-NTA column. MW = 12 KD.
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  • Gene Information
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Cat. No. : S100A6-916H
Description : S100A6 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
Source : Escherichia Coli.
Amino Acid Sequence : human mature S100A6 (Met1-Gly90). MACPLDQAIG LLVAIFHKYS GREGDKHTLS KKELKELIQK ELTIGSKLQD AEIARLMEDL DRNKDQEVNF QEYVTFLGAL ALIYNEALKG 90.
Application : Cell biology.
Purity : >95% in SDS gel.
Formulation : Lyophilized 100 μg human mature S100A6 in 50 μl of TBS ( 20 mM Tris, 50mM NaCl,pH8.0 ). Carry free.
Reconstitution : Add 500 μl deionized water or TBS to the vial to prepare a working stock solution at 200 μg/mL . Allow to set at least 30 minutes at 4° C, mix well.
Storage : Store lyophilized protein at -20 °C or -70 °C. Lyophilized protein is stable for up to 6 months from date of receipt at - 20 °C to -70 °C. Upon reconstitution, this protein can be stored at -20 °C for a few weeks or at -70 °C in a manual defrost freezer for long term storage (six months). Aliquot reconstituted protein to avoid repeated freezing / thawing cycles.
Gene Name : S100A6 S100 calcium binding protein A6 [ Homo sapiens ]
Synonyms : S100 calcium binding protein A6; 2A9; PRA; 5B10; CABP; CACY; S100A6; calcyclin; OTTHUMP00000015473; prolactin receptor-associated protein; S100 calcium-binding protein A6 (calcyclin); Calcyclin; OTTHUMP00000015472; Growth factor-inducible protein 2A9; MLN 4; Prolactin receptor-associated protein; S100 calcium-binding protein A6; S100 calcium binding protein A6 (calcyclin)
Gene ID : 6277
mRNA Refseq : NM_014624
Protein Refseq : NP_055439
MIM : 114110
UniProt ID : P06703
Chromosome Location : 1q21
Function : ion transmembrane transporter activity; protein homodimerization activity; calcium-dependent protein binding; S100 beta binding; calcium ion binding zinc ion binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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