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Recombinant Bovine PIK3R2 (Beta)

Cat.No. : PIK3R2-180B
  • Specification
  • Gene Information
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Cat. No. : PIK3R2-180B
Description : p85α acts as regulatory subunit of the class IA PI3-kinase isoforms α, β, and δ. It contains two SH2 domains that bind to tyrosine-phosphorylated growth factor receptors or substrate adaptor proteins. It also contains a BH (breakpoint cluster region homology) domain that shows GAP activity towards the small GTPases Rab4, Rab5, Cdc42, Rac1 and to a lesser extend towards Rab6 and Rab11. MW=83.5kDa.
Source : Sf9 insect cells.
Form : Liquid. Supplied in 50mM Tris-HCl pH7.5, 50mM NaCl and 50% glycerol.
Purity : >95% by SDS-PAGE.
Usage : For in vitro use only.
Storage : Quality guaranteed for 12 months. Store at -80℃. Avoid freeze / thaw cycles.
Gene Name : PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) [ Bos taurus ]
Synonyms : PIK3R2; phosphoinositide-3-kinase, regulatory subunit 2 (beta); MGC138113; phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta); phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta)
Gene ID : 282308
mRNA Refseq : NM_174576
Protein Refseq : NP_777001
UniProt ID : P23726
Chromosome Location : 7
Pathway : Acute myeloid leukemia; Apoptosis; B cell receptor signaling pathway; Chemokine signaling pathway; Chronic myeloid leukemia; Colorectal cancer; Endometrial cancer; ErbB signaling pathway; Fc epsilon RI signaling pathway; Fc gamma R-mediated phagocytosis; Focal adhesion; Glioma; Insulin signaling pathway; Jak-STAT signaling pathway; Leukocyte transendothelial migration; Melanoma; Natural killer cell mediated cytotoxicity; Neurotrophin signaling pathway; Non-small cell lung cancer; Pancreatic cancer; Pathways in cancer; Phosphatidylinositol signaling system; Prostate cancer; Regulation of actin cytoskeleton; Renal cell carcinoma; Small cell lung cancer; T cell receptor signaling pathway; Toll-like receptor signaling pathway; Type II diabetes mellitus; VEGF signaling pathway; mTOR signaling pathway
Function : 1-phosphatidylinositol-3-kinase activity; phosphoinositide 3-kinase regulator activity; protein binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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