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Cat.No.
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CABT-32548RM
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Product Overview
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Rat monoclonal antibody to Mouse CD2.
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Antigen Description
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This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
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Clone
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23-26
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Isotype
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IgG1
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Conjugation
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Fluorescein
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Immunogen
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The details of the immunogen for this antibody are not available.
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Host
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Rat
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Species
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Mouse
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Formulation
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Liquid
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Concentration
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0.500 mg/ml
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Purity Detail
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IgG fraction
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Applications
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Flow Cyt, FuncS, IP, Inhib
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Storage buffer
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Preservative: 0.1% Sodium AzideConstituents: PBS
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Storage
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Store at +4oC in the dark.
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Sequence similarities
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Contains 1 Ig-like C2-type (immunoglobulin-like) domain.Contains 1 Ig-like V-type (immunoglobulin-like) domain.
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Light chain type
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kappa
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Antigen Gene Information
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Gene name
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Cd2 CD2 antigen [ Mus musculus ]
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Official Symbol
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CD2
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Synonyms
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CD2; CD2 antigen; T-cell surface antigen CD2; CD 2; CD2; CD2 antigen (p50), sheep red blood cell receptor; CD2 antigen; CD2 molecule; CD2_HUMAN; Erythrocyte receptor; FLJ46032; LFA-2; LFA-3 receptor; LFA2; LFA3 receptor; Lymphocyte function antigen 2; OTTHUMP00000024366; p50; Rosette receptor; Sheep erythrocyte receptor; Sheep red blood cell receptor; SRBC; T cell surface antigen CD2; T cell surface antigen T11/Leu 5; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5; T11; LFA-3 receptor; OTTMUSP00000007524; lymphocyte antigen 37; T-cell surface antigen T11/Leu-5; Ly37; LFA-2; Ly-37;
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GeneID
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12481
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mRNA Refseq
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NM_013486
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Protein Refseq
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NP_038514
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Pathway
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Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; T Cell Receptor Signaling Pathway, organism-specific biosystem;
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Function
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antigen binding; eukaryotic cell surface binding; eukaryotic cell surface binding; glycoprotein binding; protein binding;
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Download Datasheet:
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