Active Recombinant Human Protein Tyrosine Phosphatase, Receptor Type, M

• Cat.No.: PTPRM-336H

Specification

• Cat. No.: PTPRM-336H
• Description: Protein Tyrosin Phosphatase, cytoplasmic region, containing catalytic domain D1 C-terminally linked to the non-catalytic domain D2. PTPmu is an Ig superfamily receptor protein-tyrosine phosphatase which promotes cell-cell adhesion in a homophilic, Ca²⁺independent manner and interacts with the cadherin-catenin complex. The intracellular region of PTPμ contains three domains: the juxtamembrane (JM, aa 765-923) and two phosphatase domains (D1 and D2). Only the D1 domain is catalitically active.
• Source: E. coli.
• Usage: For in vitro use only.
• Form: Liquid. Supplied in 10 mM Tris- HCl, 10 mM Bis-Tris-HCl pH 7.0.
• Activity: 1 nmol of PTPμ will hydrolyze 1.2 nmol of pNPP per minute at 37℃ at pH 4.8.
• Purity: > 95% by SDS-PAGE.
• Storage: Quality guaranteed for 12 months, store at -80℃. Avoid freeze / thaw cycles.

Gene Information

• Gene Name: PTPRM protein tyrosine phosphatase, receptor type, M [ Homo sapiens ]
• Synonyms: PTPRM; protein tyrosine phosphatase, receptor type, M; RPTPM; RPTPU; PTPRL1; hR-PTPu; R-PTP-MU; MGC166994; protein tyrosine phosphatase mu; protein tyrosine phosphatase, receptor type, mu polypeptide; EC 3.1.3.48
• Gene ID: 5797
• mRNA Refseq: NM_001105244
• Protein Refseq: NP_001098714
• MIM: 176888
• UniProt ID: P28827
• Chromosome Location: 18p11.2
• Pathway: Adherens junction; Cell adhesion molecules (CAMs)
• Function: cadherin binding; hydrolase activity; protein binding; receptor activity; transmembrane receptor protein tyrosine phosphatase activity