Ubiquitin Carboxyl-terminal Hydrolase 7
Cat.No. : | CBCRY35 |
- Specification
- Gene Information
- Related Products
Cat. No. : | CBCRY35 |
Background : | Herpesvirus-associated ubiquitin-specific protease (HAUSP, also known as USP7), a deubiquitylating enzyme of the ubiquitin-specific processing protease family, specifically deubiquitylates both p53 and MDM2, hence playing an important yet enigmatic role in the p53-MDM2 pathway. |
Protein Classification : | Hydrolase |
Structure Weight : | 121067.00 Da |
Polymer : | 1 |
Molecule : | Ubiquitin carboxyl-terminal hydrolase 7 |
Chain Length : | 522 amino acids |
PDB ID : | 2F1Z |
MMDB ID : | 37695 |
Source : | E.coli |
Method : | X-Ray Diffraction |
Resolution : | 3.2Å |
Reference : | Hu, M., Gu, L., Li, M., Jeffrey, P.D., Gu, W., Shi, Y. (2006) Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53-MDM2 Pathway. Plos Biol. 4: e27-e27 |
Gene Name : | USP7 |
Synonyms : | HAUSP; TEF1; EC 3.1.2.15; Herpes virus-associated ubiquitin-specific protease; ubiquitin specific peptidase 7; ubiquitin specific protease 7 (herpes virus-associated); deubiquitinating enzyme 7; Ubiquitin thioesterase 7 |
UniProt ID : | Q93009 |
Gene ID : | 7874 |
Chromosome Location : | 16p13.3 |
Function : | cysteine-type endopeptidase activity; ubiquitin thiolesterase activity; protein binding; protein C-terminus binding; peptidase activity; cysteine-type peptidase activity; hydrolase activity |
Products Types
◆ Recombinant Protein | ||
USP7-0552H | Recombinant Human USP7 Protein (K208-E560), His tagged | +Inquiry |
USP7-925H | Recombinant Human USP7 protein(Met1-Asn1102), His&GST-tagged | +Inquiry |
USP7-0553H | Recombinant Human USP7 Protein (A2-T344), Tag Free | +Inquiry |
USP7-677H | Recombinant Human USP7 Protein, MYC/DDK-tagged | +Inquiry |
Usp7-6882M | Recombinant Mouse Usp7 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
USP7-671HCL | Recombinant Human USP7 cell lysate | +Inquiry |
USP7-672HCL | Recombinant Human USP7 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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