Recombinant Human RALGDS protein, GST-tagged

• Cat.No.: RALGDS-1124H
• Product Overview: Recombinant Human RALGDS(788-885 aa) fused with GST tag was expressed in E. coli.

Specification

• Description: Guanine nucleotide dissociation stimulators (GDSs, or exchange factors), such as RALGDS, are effectors of Ras-related GTPases (see MIM 190020) that participate in signaling for a variety of cellular processes.
• Source: E. coli
• Species: Human
• Tag: GST
• Form: liquid (Supplied in 30 mM Tris-HCl pH 7.5, 100 mM NaCl, 5mM MgCl2 and 5 mM DTE)
• Molecular Mass: 40 kDa
• Purity: >90 % (SDS-PAGE)
• Storage: store at -80 centigrade. avoid freeze/thaw cycles.

Gene Information

• Gene Name: RALGDS ral guanine nucleotide dissociation stimulator [ Homo sapiens ]
• Official Symbol: RALGDS
• Synonyms: RALGDS; ral guanine nucleotide dissociation stimulator; RalGEF; RGDS; RGF; ral guanine nucleotide exchange factor; FLJ20922
• Gene ID: 5900
• mRNA Refseq: NM_006266
• Protein Refseq: NP_006257
• MIM: 601619
• UniProt ID: Q12967
• Chromosome Location: 9q34.3
• Pathway: Colorectal cancer, organism-specific biosystem; Colorectal cancer, conserved biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; ErbB1 downstream signaling, organism-specific biosystem; NGF signalling via TRKA from the plasma membrane, organism-specific biosystem; Pancreatic cancer, organism-specific biosystem; Pancreatic cancer, conserved biosystem
• Function: guanyl-nucleotide exchange factor activity; small GTPase regulator activity; small GTPase regulator activity