Polyadenylate-binding Protein 2

• Cat.No.: CBCRY37

Specification

• Cat. No.: CBCRY37
• Background: Poly(A) binding protein, nuclear 1, also known as PABPN1, is required for progressive and efficient polymerization of poly(A) tails on the 3" ends of eukaryotic genes and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm.
• Protein Classification: RNA binding protein
• Structure Weight: 43445.20 Da
• Polymer: 1
• Molecule: Polyadenylate-binding protein 2
• Chain Length: 96 amino acids
• PDB ID: 3B4M
• MMDB ID: 61872
• Source: E.coli
• Method: X-Ray Diffraction
• Resolution: 2.82Å
• Reference: Ge, H., Zhou, D., Tong, S., Gao, Y., Teng, M., Niu, L. (2008) Crystal structure and possible dimerization of the single RRM of human PABPN1 Proteins 71: 1539-1545

Gene Information

• Gene Name: PABPN1
• Synonyms: OPMD; PAB2; PABP2; poly(A) binding protein 2; poly(A) binding protein II; poly(A) binding protein, nuclear 1
• UniProt ID: Q86U42
• Gene ID: 8106
• Chromosome Location: 14q11.2-q13
• Function: nucleotide binding; nucleic acid binding; RNA binding; protein binding