Recombinant Human SRC, SH3 Domain, GST-tagged

• Cat.No.: SRC-192H

Specification

• Cat. No.: SRC-192H
• Description: N-terminal GST tagged Src SH3 domain. Src SH3 domain is the SH3 domain of Src tyrosine kinase. SH3 domains are known to bind proline rich peptides. The Src SH3 domain has been expressed as a fusion protein with GST allowing expression in E. coli and purification by affinity chromatography. The native GST-Src-SH3 is the ideal tool for in vitro/in vivo investigations of the behaviour of cellular prions. It may be used for protein-protein interaction studies as well as forin vitro/in vivoconversion studies. The GST-Tag facilitates the protein's application in typical GST pull-down assays.
• Source: E. coli.
• Form: Lyophilized.
• Purity: ≥90% by SDS-PAGE.
• Usage: For in vitro use only.
• Storage: Quality guaranteed for 12 months store at -80°C. Avoid freeze / thaw cycles.

Gene Information

• Gene Name: SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) [ Homo sapiens ]
• Synonyms: SRC; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian); ASV; SRC1; c-SRC; p60-Src; proto-oncogene tyrosine-protein kinase SRC; OTTHUMP00000174476; OTTHUMP00000174477; tyrosine kinase pp60c-src; tyrosine-protein kinase SRC-1; protooncogene SRC, Rous sarcoma; EC 2.7.10.2; pp60c-src; v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogenehomolog
• Gene ID: 6714
• mRNA Refseq: NM_005417
• Protein Refseq: NP_005408
• MIM: 190090
• UniProt ID: P12931
• Chromosome Location: 20q12-q13
• Pathway: Adherens junction; Endocytosis; Epithelial cell signaling in Helicobacter pylori infection; ErbB signaling pathway; Focal adhesion; Gap junction; GnRH signaling pathway; Tight junction; VEGF signaling pathway
• Function: ATP binding; SH2 domain binding; SH3/SH2 adaptor activity; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein binding; transferase activity