Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human DMPK, GST-tagged, Active

Cat.No. : DMPK-295H
Product Overview : Recombinant full-length human DMPK was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW=105 kDa.
  • Specification
  • Gene Information
  • Related Products
Cat. No. : DMPK-295H
Description : DMPK (or Myotonic Dystrophy Protein Kinase) is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. DMPK protein has a leucine-rich domain at the N-terminus, a serine/threonine kinase domain in the middle, and a hydrophobic region at the C-terminus. The N-terminus of DMPK plays an important role in DMPK kinase activity, and the C-terminus of DMPK determines the intracellular localization of the protein. Myotonic dystrophy type 1 is an autosomal dominant disease caused by a trinucleotide repeat-expansion, cytosine-thymine-guanine (CTG)n, in the 3" untranslated region of DMPK.
Source : Sf9 insect cellsusing baculovirus.
Sequence : Full-length.
Applications : Kinase Assay, Western Blot.
Storage And Stability : Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name : DMPK dystrophia myotonica-protein kinase [ Homo sapiens ]
Synonyms : DMPK; dystrophia myotonica-protein kinase; DM; DM1; DMK; MDPK; DM1PK; MT-PK; DM protein kinase; myotonic dystrophy protein kinase; thymopoietin homolog; myotonin protein kinase A; myotonic dystrophy associated protein kinase; EC 2.7.11.1
Gene ID : 1760
mRNA Refseq : NM_001081560
Protein Refseq : NP_001075029
MIM : 605377
UniProt ID : Q09013
Chromosome Location : 19q13.3
Function : ATP binding; magnesium ion binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; transferase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All DMPK Products

Required fields are marked with *

My Review for All DMPK Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends