Recombinant Human EPH Receptor B4, GST-tagged, Active
Cat.No. : | EPHB4-306H |
Product Overview : | Recombinant human EPHB4 (561-end) was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW=50kDa. |
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- Gene Information
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Cat. No. : | EPHB4-306H |
Description : | EPHB4 is a member of the Eph family of receptor tyrosine kinases which play a role in regulating cell adhesion and cell movement during embryonic development. Furthermore, because tissue disorganization and abnormal cell adhesion, movement, and survival characterize the more advanced stages of cancer, the inappropriate functioning of Eph receptor could play a causal role in malignancy. EPHB4 is uniquely expressed in the vascular endothelial and endocardial cells and animal knockout studies with EPHB4 reveal a phenotype that is similar to Ephrin B2 gene knockdown. Furthermore, EPHB4 has been shown to be the major essential interaction partner of Ephrin B2 in angiogenesis. |
Source : | Sf9 insect cellsusing baculovirus. |
Sequence : | 561-end. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | EPHB4 EPH receptor B4 [ Homo sapiens ] |
Synonyms : | EPHB4; EPH receptor B4; HTK; MYK1; TYRO11; ephrin receptor EphB4; soluble EPHB4 variant 1; soluble EPHB4 variant 2; soluble EPHB4 variant 3; hepatoma transmembrane kinase; EC 2.7.10.1; Tyro11; Ephrin type-B receptor 4; Tyrosine-protein kinase receptor HTK; Tyrosine-protein kinase TYRO11; EPH receptor B4; Tyrosine-protein kinase receptor HTK; ephrin receptor EphB4; hepatoma transmembrane kinase |
Gene ID : | 2050 |
mRNA Refseq : | NM_004444 |
Protein Refseq : | NP_004435 |
MIM : | 600011 |
UniProt ID : | P54760 |
Chromosome Location : | 7q22 |
Pathway : | Axon guidance |
Function : | ATP binding; ephrin receptor activity; nucleotide binding; protein binding; receptor activity; transferase activity |
Products Types
◆ Recombinant Protein | ||
EPHB4-853H | Recombinant Human EPHB4 Protein, His (Fc)-Avi-tagged | +Inquiry |
EPHB4-228H | Recombinant Human EPHB4 Protein, His-tagged | +Inquiry |
EPHB4-363H | Recombinant Human EPHB4 Protein (Met1-Ala539), His-tagged, Biotinylated | +Inquiry |
Ephb4-161M | Recombinant Mouse Ephb4 Protein, His (Fc)-Avi-tagged | +Inquiry |
EPHB4-003H | Recombinant Human EPHB4 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
EPHB4-2128MCL | Recombinant Mouse EPHB4 cell lysate | +Inquiry |
EPHB4-001HCL | Recombinant Human EPHB4 cell lysate | +Inquiry |
EPHB4-2970HCL | Recombinant Human EPHB4 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1548 | U2OS EphB4 Bioassay Kit | +Inquiry |
Kit-1585 | EphB4 Functional Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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