Recombinant Human LYNA, GST-tagged, Active
| Cat.No. : |
LYNA-344H |
| Product Overview : |
Recombinant full-length human LYN A was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW=81 kDa. |
- Specification
- Gene Information
- Related Products
| Cat. No. : |
LYNA-344H |
| Description : |
LYN A is a member of the Src-family of protein kinases that participate in signaling pathways of a variety of cell surface receptors and are localized to the cytoplasmic side of the plasma membrane. LYN A is biosynthetically transported to the plasma membrane via the Golgi pool of caveolin along the secretory pathway. The trafficking of LYN A from the Golgi apparatus to the plasma membrane is inhibited by deletion of the kinase domain but not by kinase inactivation. The kinase domain of LYN A plays a role in LYN A trafficking besides catalysis of substrate phosphorylation. cDNA microarray analysis revealed that LYN A may be involved in the changes that are related to tumor pathogenesis. |
| Source : |
Sf9 insect cellsusing baculovirus. |
| Sequence : |
Full-length. |
| Applications : |
Kinase Assay, Western Blot. |
| Storage And Stability : |
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
| Gene Name : |
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog [ Homo sapiens ] |
| Synonyms : |
LYN; v-yes-1 Yamaguchi sarcoma viral related oncogene homolog; JTK8; FLJ26625; Yamaguchi sarcoma viral (v-yes-1) related oncogene homolog; EC 2.7.10.2 |
| Gene ID : |
4067 |
| mRNA Refseq : |
NM_001111097 |
| Protein Refseq : |
NP_001104567 |
| MIM : |
165120 |
| UniProt ID : |
P07948 |
| Chromosome Location : |
8q13 |
| Pathway : |
B cell receptor signaling pathway; Chemokine signaling pathway; Epithelial cell signaling in Helicobacter pylori infection; Fc epsilon RI signaling pathway; Fc gamma R-mediated phagocytosis; Hemostasis; Signaling in Immune system; Fc epsilon RI signaling pathway |
| Function : |
ATP binding; glycosphingolipid binding; integrin binding; non-membrane spanning protein tyrosine kinase activity; phosphoprotein binding; platelet-derived growth factor receptor binding; receptor signaling protein tyrosine kinase activity; transferase activity; ubiquitin protein ligase binding |
Products Types
Related Gene
LYNA
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
