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Cat.No.
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CABT-35927MH
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Product Overview
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Mouse monoclonal antibody to Human P2RX5.
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Antigen Description
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The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. This gene encodes chaperonin cofactor A.
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Isotype
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IgG1
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Immunogen
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Recombinant fragment: DGACSKDSDC HAGEAVTAGN GVKTGRCLRR ENLARGTCEI FAWCPLETSS RPEEPFLKEA EDFTIFIKNH IRFPKFNFSK SNVMDVKDRS FLKSCHFGP, corresponding to amino acids 126-225 of Human P2X5b
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Host
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Mouse
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Species
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Human
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Formulation
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Liquid
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Concentration
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1.000 mg/ml
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Purity Detail
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Protein G purified
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Applications
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WB
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Storage buffer
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Preservative: NonePBS, pH 7.2
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Storage
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Shipped at 4oC. Upon delivery aliquot and store at -20oC or -80oC. Avoid repeated freeze / thaw cycles.
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Light chain type
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kappa
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Antigen Gene Information
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Gene name
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P2RX5 purinergic receptor P2X, ligand-gated ion channel, 5 [ Homo sapiens ]
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Official Symbol
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P2RX5
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Synonyms
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P2RX5; purinergic receptor P2X, ligand-gated ion channel, 5; P2X purinoceptor 5; P2X5; ATP receptor; ATP receptor subunit; ionotropic ATP receptor P2X5; MGC47755; P2RX5; P2X purinoceptor 5; P2X5; P2X5R; Purinergic receptor; Purinergic receptor P2X ligand gated ion channel 5; OTTHUMP00000115870; OTTHUMP00000241718; OTTHUMP00000241719; OTTHUMP00000241720; OTTHUMP00000241722; OTTHUMP00000241723; ATP receptor subunit; ionotropic ATP receptor P2X5; lymphoid-restricted histocompatibility antigen-1; LRH-1; P2X5R;
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GeneID
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5026
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mRNA Refseq
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NM_001204519
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Protein Refseq
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NP_001191448
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MIM
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602836
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Uniprot ID
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Q93086
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Chromosome Location
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17p13.3
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Pathway
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Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
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Function
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ATP binding; extracellular ATP-gated cation channel activity; extracellular ATP-gated cation channel activity; ion channel activity; purinergic nucleotide receptor activity;
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Download Datasheet:
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