Recombinant Human CAMKK1, GST-tagged, Active
Cat.No. : | CAMKK1-269H |
Product Overview : | Recombinant full-length human CAMKK1 was expressed by baculovirus inSf9insect cells using a N-terminal GST tag. MW = 94 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CAMKK1-269H |
Description : | CAMKK1 or CAMKKα is a Ca(2+)/calmodulin-dependent protein kinase that activates CaM-kinases I and IV via phosphorylation of their Thr(177) and Thr(196) residues, respectively. Recent studies have shown that the activity of CAMKK1 is decreased upon phosphorylation by cAMP-dependent protein kinase (PKA) The CAMKKalpha has been identified in intact cells as AMPKKs, predicting a significant role for this kinase in regulating AMPK activity in vivo. It has been shown that 2-deoxyglucose- and ionomycin-stimulated AMPK activity is substantially reduced in HeLa cells transfected with small interfering RNAs specific for CAMKKα. |
Source : | Sf9 insect cells using baculovirus. |
Sequence : | Full-length. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha [ Homo sapiens ] |
Synonyms : | CAMKK1; calcium/calmodulin-dependent protein kinase kinase 1, alpha; CAMKKA; MGC34095; DKFZp761M0423; calcium/calmodulin-dependent protein kinase 1 alpha; CAMKK alpha protein; EC 2.7.11.17; OTTHUMP00000115904; Calcium/calmodulin-dependent protein kinase kinase alpha; CaM-KK alpha; CaM-kinase IV kinase; CaM-kinase kinase alpha; CaMKK alpha |
Gene ID : | 84254 |
mRNA Refseq : | NM_032294 |
Protein Refseq : | NP_115670 |
MIM : | 611411 |
UniProt ID : | Q8N5S9 |
Chromosome Location : | 17p13.2 |
Pathway : | Adipocytokine signaling pathway |
Function : | ATP binding; calmodulin binding; calmodulin-dependent protein kinase activity; nucleotide binding; IEA; transferase activity |
Products Types
◆ Recombinant Protein | ||
Camkk1-1946M | Recombinant Mouse Camkk1 Protein, Myc/DDK-tagged | +Inquiry |
CAMKK1-771R | Recombinant Rat CAMKK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CAMKK1-0338H | Active Recombinant Human CAMKK1 Protein, GST-Tagged | +Inquiry |
CAMKK1-0172H | Recombinant Human CAMKK1 Protein (M1-S505), His tagged | +Inquiry |
CAMKK1-0171H | Recombinant Human CAMKK1 Protein (M1-S505), Tag Free | +Inquiry |
◆ Lysates | ||
CAMKK1-7874HCL | Recombinant Human CAMKK1 293 Cell Lysate | +Inquiry |
CAMKK1-7873HCL | Recombinant Human CAMKK1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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