Recombinant Human CDK1/Cyclin A2, GST-tagged, Active
Cat.No. : | CDK1/CyclinA2-271H |
Product Overview : | Recombinant full-length human CDK1 and CyclinA2 were co-expressed by baculovirus inSf9insect cells using an N-terminal GST tag on both proteins. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CDK1/Cyclin A2-271H |
Description : | CDK1 or Cell Division Control protein 1 is essential for the completion of START, the controlling event in the cell cycle that is required to initiate mitosis. CDK1 is a catalytic subunit of a protein kinase complex, called the M-Phase Promoting Factor that induces entry into mitosis and is universal among eukaryotes. Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis. Therapeutic potential of CDK inhibitor NU2058 in androgen-independent prostate cancer has also been demonstrated. |
Source : | Sf9 insect cells using baculovirus. |
Molecular Weight : | ~59 kDa and CyclinA2 ~78 kDa. |
Sequence : | Full-length. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | CDK1 cyclin-dependent kinase 1 [ Homo sapiens ]CCNA2 cyclin A2 [ Homo sapiens ] |
Synonyms : | CDK1; cyclin-dependent kinase 1; CDC2; CDC28A; P34CDC2; MGC111195; DKFZp686L20222; cell division cycle 2; OTTHUMP00000019659; OTTHUMP00000019660; OTTHUMP00000019661; p34 protein kinase; cell cycle controller CDC2; cell division control protein 2 homolog; cell division cycle 2, G1 to S and G2 to M; EC 2.7.11.23; EC 2.7.11.22; CCNA2; cyclin A2; CCN1; CCNA; Cyclin-A; Cyclin-A2 |
Gene ID : | 983890 |
mRNA Refseq : | NM_001170406NM_001237 |
Protein Refseq : | NP_001163877NP_001228 |
MIM : | 116940123835 |
UniProt ID : | P06493P20248 |
Chromosome Location : | 10q21.14q25-q31 |
Pathway : | Cell cycle; Gap junction; Progesterone-mediated oocyte maturation; p53 signaling pathway; Cell cycle; Progesterone-mediated oocyte maturation |
Function : | ATP binding; RNA polymerase II carboxy-terminal domain kinase activity; cyclin-dependent protein kinase activity; cyclin-dependent protein kinase activity; nucleotide binding; protein binding; transferase activity; protein binding |
Products Types
◆ Recombinant Protein | ||
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CDK1-561H | Recombinant Human CDK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDK1-3143H | Recombinant Human CDK1 Protein, MYC/DDK-tagged | +Inquiry |
CDK1-653H | Recombinant Human CDK1 protein, His-tagged | +Inquiry |
◆ Lysates | ||
CDK1-001MCL | Recombinant Mouse CDK1 cell lysate | +Inquiry |
CDK1-670HCL | Recombinant Human CDK1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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