Recombinant Human CDK2/Cyclin A2, GST-tagged, Active
Cat.No. : | CDK2/CyclinA2-272H |
Product Overview : | Recombinant full-length human CDK2 and CyclinA2 were co-expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag on both proteins. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CDK2/Cyclin A2-272H |
Description : | CDK2 is a member of the Cyclin-Dependent Kinase family that is ubiquitously expressed. CDK2 is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. CDK2 associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). CDK2 phosphorylates multiple cellular substrates including SMAD3 and FOXO1. Phosphorylation of FOXO1 leads to its inhibition. |
Source : | Sf9 insect cells using baculovirus. |
Molecular Weight : | ~58 kDa and CyclinA2 ~78 kDa. |
Sequence : | Full-length. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | CDK2 cyclin-dependent kinase 2 [ Homo sapiens ]CCNA2 cyclin A2 [ Homo sapiens ] |
Synonyms : | CDK2; cyclin-dependent kinase 2; p33 protein kinase; cell devision kinase 2; cdc2-related protein kinase; EC 2.7.11.22; cell devision protein kinase 2;CCNA2; p33(CDK2); cyclin A2; CCN1; CCNA; Cyclin-A; Cyclin-A2 |
Gene ID : | 1017890 |
mRNA Refseq : | NM_001798NM_001237 |
Protein Refseq : | NP_001789NP_001228 |
MIM : | 116953123835 |
UniProt ID : | P24941P20248 |
Chromosome Location : | 12q134q25-q31 |
Pathway : | Cell cycle; Pathways in cancer; ; Progesterone-mediated oocyte maturation; Prostate cancer; Small cell lung cancer; p53 signaling pathway |
Function : | ATP binding; cyclin-dependent protein kinase activity; histone kinase activity; identical protein binding; nucleotide binding; transferase activity; protein binding |
Products Types
◆ Recombinant Protein | ||
CDK2-1521M | Recombinant Mouse CDK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDK2-562H | Recombinant Human CDK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDK2-726H | Recombinant Human CDK2 Protein, His-tagged | +Inquiry |
Cdk2-864M | Recombinant Mouse Cdk2 Protein, MYC/DDK-tagged | +Inquiry |
CDK2-1000H | Recombinant Human CDK2 Protein, GST-Tagged | +Inquiry |
◆ Lysates | ||
CDK2-708HCL | Recombinant Human CDK2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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