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Recombinant Human B lymphoid Tyrosine Kinase, GST-tagged, Active

Cat.No. : BLK-250H
Product Overview : Recombinant full-length human BLK was expressed by baculovirus inSf9 insect cellsusing a N-terminal GST tag. MW = 84 kDa.
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Cat. No. : BLK-250H
Description : BLK, also known as B lymphoid kinase, is a 55 kd tyrosine kinases with a SH3, SH2 and catalytic domains that contain consensus sequences of the src protein tyrosine kinase family. BLK is expressed specifically in the B cell lineage and plays a role in signal transduction pathway that is restricted to B lymphoid cells. Stimulation of resting B-lymphocytes with antibodies to surface immunoglobulin (sIgD or sIgM) induces activation of BLK.
Source : Sf9 insect cells using baculovirus.
Sequence : Full-length.
Applications : Kinase Assay, Western Blot.
Storage And Stability : Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name : BLK B lymphoid tyrosine kinase [ Homo sapiens ]
Synonyms : B lymphoid tyrosine kinase;MGC10442; BLK; BLK nonreceptor tyrosine kinase; EC 2.7.10.2; p55-BLK; B lymphocyte kinase
Gene ID : 640
mRNA Refseq : NM_001715
Protein Refseq : NP_001706
MIM : 191305
UniProt ID : P51451
Chromosome Location : 8p23-p22
Function : non-membrane spanning protein tyrosine kinase activity; ATP binding; nucleotide binding; protein binding; transferase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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