Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human MKNK2, GST-tagged, Active

Cat.No. : MKNK2-356H
Product Overview : Recombinant full-length human MNK2 was expressed by baculovirus inSf9insect cells using a N-terminal GST tag. MW = 74 kDa.
  • Specification
  • Gene Information
  • Related Products
Cat. No. : MKNK2-356H
Description : MNK2 (MAP kinase-interacting kinase 2) contains a conserved C-terminal ERK-interacting domain, a catalytic domain with homology to the calcium/calmodulin-dependent family of kinases, and putative MAP kinase phosphorylation sites located within the T loop of the kinase domain. MNK2 binds tightly to the growth factor-regulated MAP kinases, ERK1 and ERK2. ERK and p38 phosphorylate MNK2, which stimulates its in vitro kinase activity toward a substrate, eukaryotic initiation factor-4E (eIF-4E). A yeast two-hybrid screen showed the Mnk2 protein interacted with the ligand-binding domain of estrogen receptor beta (ERbeta).
Source : Sf9 insect cells using baculovirus.
Sequence : Full-length.
Applications : Kinase Assay, Western Blot.
Storage And Stability : Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name : MKNK2 MAP kinase interacting serine/threonine kinase 2 [ Homo sapiens ]
Synonyms : MKNK2; MAP kinase interacting serine/threonine kinase 2; MNK2; GPRK7; MAP kinase-interacting serine/threonine kinase 2; G protein-coupled receptor kinase 7; Putative map kinase interacting kinase; EC 2.7.11.1; MAP kinase signal-integrating kinase 2; Mnk2
Gene ID : 2872
mRNA Refseq : NM_017572
Protein Refseq : NP_060042
MIM : 5069
UniProt ID : Q9HBH9
Chromosome Location : 19p13.3
Pathway : Insulin signaling pathway; MAPK signaling pathway
Function : ATP binding; magnesium ion binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; transferase activity; zinc ion binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All MKNK2 Products

Required fields are marked with *

My Review for All MKNK2 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends