Recombinant Human MKNK2, GST-tagged, Active
Cat.No. : | MKNK2-356H |
Product Overview : | Recombinant full-length human MNK2 was expressed by baculovirus inSf9insect cells using a N-terminal GST tag. MW = 74 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | MKNK2-356H |
Description : | MNK2 (MAP kinase-interacting kinase 2) contains a conserved C-terminal ERK-interacting domain, a catalytic domain with homology to the calcium/calmodulin-dependent family of kinases, and putative MAP kinase phosphorylation sites located within the T loop of the kinase domain. MNK2 binds tightly to the growth factor-regulated MAP kinases, ERK1 and ERK2. ERK and p38 phosphorylate MNK2, which stimulates its in vitro kinase activity toward a substrate, eukaryotic initiation factor-4E (eIF-4E). A yeast two-hybrid screen showed the Mnk2 protein interacted with the ligand-binding domain of estrogen receptor beta (ERbeta). |
Source : | Sf9 insect cells using baculovirus. |
Sequence : | Full-length. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | MKNK2 MAP kinase interacting serine/threonine kinase 2 [ Homo sapiens ] |
Synonyms : | MKNK2; MAP kinase interacting serine/threonine kinase 2; MNK2; GPRK7; MAP kinase-interacting serine/threonine kinase 2; G protein-coupled receptor kinase 7; Putative map kinase interacting kinase; EC 2.7.11.1; MAP kinase signal-integrating kinase 2; Mnk2 |
Gene ID : | 2872 |
mRNA Refseq : | NM_017572 |
Protein Refseq : | NP_060042 |
MIM : | 5069 |
UniProt ID : | Q9HBH9 |
Chromosome Location : | 19p13.3 |
Pathway : | Insulin signaling pathway; MAPK signaling pathway |
Function : | ATP binding; magnesium ion binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; transferase activity; zinc ion binding |
Products Types
◆ Recombinant Protein | ||
MKNK2-33H | Recombinant Human MKNK2 Protein (D228G, 72-385), His tagged | +Inquiry |
MKNK2-5369H | Recombinant Human MKNK2 Protein, GST-tagged | +Inquiry |
MKNK2-1165H | Recombinant Human MKNK2 Protein (T72-R385), His tagged | +Inquiry |
MKNK2-1164H | Recombinant Human MKNK2 Protein (T72-R385), Tag Free | +Inquiry |
MKNK2-1416H | Recombinant Human MKNK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
MKNK2-4301HCL | Recombinant Human MKNK2 293 Cell Lysate | +Inquiry |
MKNK2-4302HCL | Recombinant Human MKNK2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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