Recombinant Human CDC42BPB, GST-tagged, Active

• Cat.No.: CDC42BPB-358H
• Product Overview: Recombinant human MRCKbeta (1-473) was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW = 73 kDa.

Specification

• Cat. No.: CDC42BPB-358H
• Description: Myotonic Dystrophy Kinase-Related cdc42-binding kinase beta (MRCKβ) belongs to the DMPK subfamily. The myotonic dystrophy kinase-related kinases and myotonic dystrophy kinase-related Cdc42 binding kinase (MRCK) are effectors of RhoA and Cdc42, respectively, where they are involved in actin cytoskeletal reorganization and neurite outgrowth. Effects of the repeat expansion on the DMPK gene may be responsible for muscle and heart features of Myotonic Dystrophy.
• Source: Sf9 insect cells using baculovirus.
• Sequence: 1-473.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: CDC42BPB CDC42 binding protein kinase beta (DMPK-like) [ Homo sapiens ]
• Synonyms: CDC42BPB; CDC42 binding protein kinase beta (DMPK-like); MRCKB; KIAA1124; CDC42-binding protein kinase beta; myotonic dystrophy protein kinase-like beta; CDC42-binding protein kinase beta (DMPK-like); EC 2.7.11.1; DMPK-like beta; MRCK beta; Myotonic dystrophy kinase-related CDC42-binding kinase beta; Serine/threonine-protein kinase MRCK beta
• Gene ID: 9578
• mRNA Refseq: NM_006035
• Protein Refseq: NP_006026
• UniProt ID: Q9Y5S2
• Chromosome Location: 14q32.3
• Function: ATP binding; Rho GTPase binding; magnesium ion binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; small GTPase regulator activity; transferase activity; zinc ion binding