Recombinant Human MAPK13, GST-tagged, Active

• Cat.No.: MAPK13-374H
• Product Overview: Recombinant full-length human MAPK13 was expressed bybaculovirusinSf9 insect cellsusing an N-terminal GST tag. MW=71 kDa.

Specification

• Cat. No.: MAPK13-374H
• Description: P38δ (SAPK4) is a member of the p38 MAPK family and is activated by chemical and environmental stresses as well as by proinflammatory cytokines. P38δ has a TGY dual phosphorylation motif and is activated in response to cellular stresses and proinflammatory cytokines. MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase.
• Source: Sf9 insect cells using baculovirus.
• Sequence: Full-length.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: MAPK13 mitogen-activated protein kinase 13 [ Homo sapiens ]
• Synonyms: MAPK13; mitogen-activated protein kinase 13; SAPK4; PRKM13; MGC99536; p38delta; stress-activated protein kinase 4; mitogen-activated protein kinase p38 delta; mitogen activated protein kinase 13; EC 2.7.11.24
• Gene ID: 5603
• mRNA Refseq: NM_002754
• Protein Refseq: NP_002745
• MIM: 602899
• UniProt ID: O15264
• Chromosome Location: 6p21.31
• Pathway: Amyotrophic lateral sclerosis (ALS); Epithelial cell signaling in Helicobacter pylori infection; Fc epsilon RI signaling pathway; GnRH signaling pathway; Leukocyte transendothelial migration; MAPK signaling pathway; Neurotrophin signaling pathway; RIG-I-like receptor signaling pathway; T cell receptor signaling pathway; Toll-like receptor signaling pathway; VEGF signaling pathway; Signalling by NGF
• Function: ATP binding; MAP kinase activity; MAP kinase kinase activity; MP kinase activity; nucleotide binding; protein binding; protein serine/threonine kinase activity; protein serine/threonine kinase activity; transferase activity