Recombinant Human RPS6KA1, GST-tagged, Active
Cat.No. : | RPS6KA1-424H |
Product Overview : | Recombinant full-length human RPS6KA1 was expressed bybaculovirusinSf9 insect cellsusing an N-terminal GST tag. MW=108kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | RPS6KA1-424H |
Description : | RSK1 is a member of the RSK (ribosomal S6 kinase) family that are growth factor-regulated serine/threonine kinases. RSK1 contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. RSK1 encodes a predicted 735-amino acid protein containing 2 distinct consensus ATP-binding site sequences. RSK1 transcript is present in lymphocytes, skeletal muscle, liver, and adipose tissue. RSKs are implicated in the activation of the mitogen-activated kinase (MAPK) cascade and the stimulation of cell proliferation and differentiation. |
Source : | Sf9 insect cells using baculovirus. |
Sequence : | Full-length. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
nullValue_other : | Long-term potentiation; MAPK signaling pathway; Neurotrophin signaling pathway; Progesterone-mediated oocyte maturation; mTOR signaling pathway; Signalling by NGF |
Gene Name : | RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 [ Homo sapiens ] |
Synonyms : | RPS6KA1; ribosomal protein S6 kinase, 90kDa, polypeptide 1; S6K-alpha 1; dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1); p90-RSK 1; ribosomal protein S6 kinase alpha 1; RSK; HU-1; RSK1; MAPKAPK1A; EC 2.7.11.1 |
Gene ID : | 6195 |
mRNA Refseq : | NM_001006665 |
Protein Refseq : | NP_001006666 |
MIM : | 601684 |
UniProt ID : | Q15418 |
Chromosome Location : | 1p |
Function : | ATP binding; magnesium ion binding; nucleotide binding; protein binding; transferase activity; protein serine/threonine kinase activity |
Products Types
◆ Recombinant Protein | ||
Rps6ka1-5609M | Recombinant Mouse Rps6ka1 Protein, Myc/DDK-tagged | +Inquiry |
RPS6KA1-4831R | Recombinant Rat RPS6KA1 Protein, His (Fc)-Avi-tagged | +Inquiry |
RPS6KA1-1149H | Recombinant Human RPS6KA1 Protein (Q33-T353), His tagged | +Inquiry |
RPS6KA1-4010H | Recombinant Human RPS6KA1 Protein, His (Fc)-Avi-tagged | +Inquiry |
RPS6KA1-1148H | Recombinant Human RPS6KA1 Protein (Q33-T353), Tag Free | +Inquiry |
◆ Lysates | ||
RPS6KA1-2162HCL | Recombinant Human RPS6KA1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionDysregulation of RPS6KA1 impacts metabolic processes, influencing conditions like diabetes and obesity.
RPS6KA1 modulates the cell cycle and apoptosis, playing a role in cell proliferation and programmed cell death.
RPS6KA1 is involved in neuronal development and function, affecting processes like learning and memory.
Genetic mutations in RPS6KA1 are linked to certain cancers and diseases, affecting its kinase activity and signaling functions.
RPS6KA1 interacts with various kinases and signaling molecules, integrating multiple cellular signaling pathways.
RPS6KA1 plays a crucial role in stress responses in cancer cells, influencing cell survival and adaptation mechanisms.
RPS6KA1 regulates protein synthesis and cell growth by modulating the mTOR pathway, affecting ribosomal protein activity.
Customer Reviews (3)
Write a reviewExceptional protein purification, highly recommended for research.
Dependable mass spectrometry analysis; enhances our proteomics research.
Quick and precise protein expression, a valuable service.
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