Catalog # or name ...
Mouse monoclonal antibody to Human TNFRSF11B.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
Synthetic peptide: TQETFPPKYLHYDEETSH, corresponding to amino acids 20-37 of Human TNFRSF11B
Protein G purified
Preservative: 0.05% Sodium AzideConstituents: 0.2% Gelatin, PBS
Shipped at 4oC. Upon delivery aliquot and store at -20oC or -80oC. Avoid repeated freeze / thaw cycles.
Contains 2 death domains.Contains 4 TNFR-Cys repeats.
Antigen Gene Information
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b [ Homo sapiens ]
TNFRSF11B; tumor necrosis factor receptor superfamily, member 11b; OPG, osteoprotegerin; tumor necrosis factor receptor superfamily member 11B; OCIF; TR1; OCIF; OPG; Osteoclastogenesis inhibitory factor; Osteoprotegerin; TNFRSF11B; TR1; TR11B_HUMAN; Tumor necrosis factor receptor superfamily member 11B; Tumor necrosis factor receptor superfamily, member 11b; osteoprotegerin; OTTHUMP00000228056; osteoclastogenesis inhibitory factor; OPG;
Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Monoamine Transport, organism-specific biosystem; Osteoblast Signaling, organism-specific biosystem; Osteoclast Signaling, organism-specific biosystem;
binding; cytokine activity; receptor activity;
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