Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human NTRK1, GST-tagged, Active

Cat.No. : NTRK1-448H
Product Overview : Recombinant human TRKA (440-end) was expressed by baculovirus inSf9 insect cellsusing a N-terminal GST tag. MW = 66kDa.
  • Specification
  • Gene Information
  • Related Products
Cat. No. : NTRK1-448H
Description : TRKA is a member of the trk proto-oncogene family and encodes a 140-kilodalton, membrane-spanning protein tyrosine kinase that is the functional receptor for nerve growth factor (NGF). NGF elicits the rapid phosphorylation of gp140trk on tyrosine residues leading to increased c-Fos expression, DNA synthesis and morphologic transformation. A decreased expression of TRKA on the striatal cholinergic neurons has been observed which may contribute, when it reaches a crucial threshold, to the death of cholinergic neurons observed in Alzheimer.
Source : Sf9 insect cells using baculovirus.
Sequence : 440-end.
Applications : Kinase Assay, Western Blot.
Storage And Stability : Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name : NTRK1 neurotrophic tyrosine kinase, receptor, type 1 [ Homo sapiens ]
Synonyms : NTRK1; neurotrophic tyrosine kinase, receptor, type 1; MTC; TRK; TRK1; TRKA; p140-TrkA; DKFZp781I14186; Trk-A; Oncogene TRK; tyrosine kinase receptor A; high affinity nerve growth factor receptor; EC 2.7.10.1
Gene ID : 4914
mRNA Refseq : NM_001007792
Protein Refseq : NP_001007793
MIM : 191315
UniProt ID : P04629
Chromosome Location : 1q21-q22
Pathway : Apoptosis; Endocytosis; MAPK signaling pathway; Neurotrophin signaling pathway; Pathways in cancer; Thyroid cancer; Signalling by NGF
Function : ATP binding; neurotrophin receptor activity; nucleotide binding; protein binding; transferase activity; transmembrane receptor protein tyrosine kinase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All NTRK1 Products

Required fields are marked with *

My Review for All NTRK1 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends