Recombinant full length Human ADAM2, isoform 2 with N terminal proprietary tag. Predicted MW 104.76 kDa.
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions.
716 amino acids
104.760kDa inclusive of tags
Expressed specifically in spermatogenic cells in the seminiferous cells. Not detected in fetal tissues.
pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids:
MWRVLFLLSGLGGLRMDSNFDSLPVQITVPEKIRSIIKEG IESQASYKIVIEGKPYTVNLMQKNFLPHNFRVYSYSGTGI MKPLDQDFQNFCHYQGYIEGYPKSVVMVSTCTGLRGVLQF ENVSYGIEPLESSVGFEHVIYQVKHKKADVSLYNEKDIES RDLSFKLQSVEYNHMGSDTTVVAQKVFQLIGLTNAIFVSF NITIILSSLELWIDENKIATTGEANELLHTFLRWKTSYLV LRPHDVAFLLVYREKSNYVGATFQGKMCDANYAGGVVLHP RTISLESLAVILAQLLSLSMGITYDDINKCQCSGAVCIMN PEAIHFSGVKIFSNCSFEDFAHFISKQKSQCLHNQPRLDP FFKQQAVCGNAKLEAGEECDCGTEQDCALIGETCCDIATC RFKAGSNCAEGPCCENCLFMSKERMCRPSFEECDLPEYCN GSSASCPENHYVQTGHPCGLNQWICIDGVCMSGDKQCTDT FGKEVEFGPSECYSHLNSKTDVSGNCGISDSGYTQCEADN LQCGKLICKYVGKFLLQIPRATIIYANISGHLCIAVEFAS DHADSQKMWIKDGTSCGSNKVCRNQRCVSSSYLGYDCTTD KCNDRGVCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSG NFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIF CVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG
Contains 1 disintegrin domain.Contains 1 EGF-like domain.Contains 1 peptidase M12B domain.