Recombinant full length Human Adiponectin, expressed in HEK293 cells, with a C terminal N-DYKDDDDK tag.
This gene is expressed in adipose tissue exclusively. It encodes a protein with similarity to collagens X and VIII and complement factor C1q. The encoded protein circulates in the plasma and is involved with metabolic and hormonal processes. Mutations in this gene are associated with adiponectin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Synthesized exclusively by adipocytes and secreted into plasma.
Lyophilised:Add deionized water to prepare a working stock solution of approximately 0.5 mg/mL and let the lyophilized pellet dissolve completely.
Preservative: NoneConstituents: 20mM Sodium chloride, 20mM Tris, pH 7.5
Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids:
ETTTQGPGVL LPLPKGACTG WMAGIPGHPG HNGAPGRDGR DGTPGEKGEKGDPGLIGPKG DIGETGVPGA EGPRGFPGIQ GRKGEPGEGA YVYRSAFSVGLETYVTIPNM PIRFTKIFYN QQNHYDGSTG KFHCNIPGLY YFAYHIVYMKDVKVSLFKKD KAMLFTYDQY QENNVDQASG SVLLHLEVGD QVWLQVYGEGERNGLYADND NDSTFTGFLL YHDTN -DYKDD DDK
Contains 1 C1q domain.Contains 1 collagen-like domain.