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Recombinant Human AFF1

Cat.No. : AFF1-26446TH
Product Overview : Recombinant fragment of Human AF4 protein with an N terminal proprietary tag; Predicted MW 36.63 kDa.
  • Specification
  • Gene Information
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Protein length : 100 amino acids
Molecular Weight : 36.630kDa inclusive of tags
Source : Wheat germ
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : LSTKSHTHRLDASENRLGKPKYPLI PDKGSSIPSSSFHTSVHHQSIHTPA SGPLSVGNISHNPKMAQPRTEPMPS LHAKSCGPPDSQHLTQDRLGQEGFG
Sequence Similarities : Belongs to the AF4 family.
Gene Name : AFF1 AF4/FMR2 family, member 1 [ Homo sapiens ]
Official Symbol : AFF1
Synonyms : AFF1; AF4/FMR2 family, member 1; MLLT2, myeloid/lymphoid or mixed lineage leukemia (trithorax (Drosophila) homolog); translocated to, 2 , PBM1, pre B cell monocytic leukemia partner 1; AF4/FMR2 family member 1; AF 4; AF4;
Gene ID : 4299
mRNA Refseq : NM_001166693
Protein Refseq : NP_001160165
MIM : 159557
Uniprot ID : P51825
Chromosome Location : 4q21.3
Pathway : Transcriptional misregulation in cancers, organism-specific biosystem; Transcriptional misregulation in cancers, conserved biosystem;
Function : sequence-specific DNA binding transcription factor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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Can AFF1 protein be targeted or manipulated to modulate gene expression or disease phenotypes, and what are the potential implications for therapeutic interventions? 11/07/2021

AFF1 protein holds potential as a target for modulating gene expression or disease phenotypes, and further research is needed to explore its implications for therapeutic interventions.

Are there any genetic variations or mutations in the gene encoding AFF1 protein that impact its expression or function, and what are the implications for cellular processes or disease susceptibility? 05/11/2021

Genetic variations or mutations in the gene encoding AFF1 protein may impact its expression or function, influencing cellular processes or disease susceptibility.

How does AFF1 protein contribute to cellular processes such as development, differentiation, or disease progression, and what are the underlying molecular mechanisms? 10/08/2020

AFF1 protein contributes to cellular processes such as development, differentiation, or disease progression, and the underlying molecular mechanisms are currently being investigated.

What experimental techniques or assays have been used to study the functional significance of AFF1 protein, such as chromatin immunoprecipitation, RNA-seq, or gene knockdown approaches? 05/23/2018

Various experimental techniques or assays, such as chromatin immunoprecipitation, RNA-seq, or gene knockdown approaches, have been used to study the functional significance of AFF1 protein.

Are there any known post-translational modifications or regulatory mechanisms that modulate the activity or stability of AFF1 protein? 07/05/2017

Post-translational modifications and regulatory mechanisms may modulate the activity or stability of AFF1 protein.

How does dysregulation or dysfunction of AFF1 protein affect transcriptional regulation, gene expression networks, or disease development? 03/22/2017

Dysregulation or dysfunction of AFF1 protein can affect transcriptional regulation, perturb gene expression networks, and contribute to disease development.

How is the expression of AFF1 protein regulated, and what factors or signaling pathways control its expression? 08/16/2015

The expression of AFF1 protein is regulated by specific factors and signaling pathways.

What is the role of AFF1 protein in gene transcription or chromatin remodeling, and how can its function be investigated experimentally? 05/02/2015

AFF1 protein plays a role in gene transcription or chromatin remodeling, and its function can be investigated using techniques like chromatin immunoprecipitation or gene expression analysis.

What is the subcellular localization of AFF1 protein, and how can it be experimentally determined? 04/25/2015

The subcellular localization of AFF1 protein can be experimentally determined using techniques such as immunofluorescence microscopy or subcellular fractionation.

Does AFF1 protein interact with specific molecules or participate in protein complexes, and what are the functional implications of these interactions? 04/12/2015

AFF1 protein may interact with specific molecules or participate in protein complexes, which have functional implications in cellular processes.

Customer Reviews (3)

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Reviews
12/15/2021

    Investigating protein-protein interactions in cellular senescence for aging-related diseases.

    04/07/2019

      Mapping protein-protein interactions in immune checkpoint regulation for immunotherapy.

      03/18/2017

        Unraveling protein-protein interactions in RNA splicing for gene expression regulation.

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