Recombinant Human AFF1
Cat.No. : | AFF1-26446TH |
Product Overview : | Recombinant fragment of Human AF4 protein with an N terminal proprietary tag; Predicted MW 36.63 kDa. |
- Specification
- Gene Information
- Related Products
Protein length : | 100 amino acids |
Molecular Weight : | 36.630kDa inclusive of tags |
Source : | Wheat germ |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | LSTKSHTHRLDASENRLGKPKYPLI PDKGSSIPSSSFHTSVHHQSIHTPA SGPLSVGNISHNPKMAQPRTEPMPS LHAKSCGPPDSQHLTQDRLGQEGFG |
Sequence Similarities : | Belongs to the AF4 family. |
Gene Name : | AFF1 AF4/FMR2 family, member 1 [ Homo sapiens ] |
Official Symbol : | AFF1 |
Synonyms : | AFF1; AF4/FMR2 family, member 1; MLLT2, myeloid/lymphoid or mixed lineage leukemia (trithorax (Drosophila) homolog); translocated to, 2 , PBM1, pre B cell monocytic leukemia partner 1; AF4/FMR2 family member 1; AF 4; AF4; |
Gene ID : | 4299 |
mRNA Refseq : | NM_001166693 |
Protein Refseq : | NP_001160165 |
MIM : | 159557 |
Uniprot ID : | P51825 |
Chromosome Location : | 4q21.3 |
Pathway : | Transcriptional misregulation in cancers, organism-specific biosystem; Transcriptional misregulation in cancers, conserved biosystem; |
Function : | sequence-specific DNA binding transcription factor activity; |
Products Types
◆ Recombinant Protein | ||
Aff1-3230M | Recombinant Mouse Aff1, His-tagged | +Inquiry |
AFF1-405H | Recombinant Human AFF1 Protein, GST-tagged | +Inquiry |
AFF1-1732H | Recombinant Human AFF1 protein, His & T7-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (10)
Ask a questionAFF1 protein holds potential as a target for modulating gene expression or disease phenotypes, and further research is needed to explore its implications for therapeutic interventions.
Genetic variations or mutations in the gene encoding AFF1 protein may impact its expression or function, influencing cellular processes or disease susceptibility.
AFF1 protein contributes to cellular processes such as development, differentiation, or disease progression, and the underlying molecular mechanisms are currently being investigated.
Various experimental techniques or assays, such as chromatin immunoprecipitation, RNA-seq, or gene knockdown approaches, have been used to study the functional significance of AFF1 protein.
Post-translational modifications and regulatory mechanisms may modulate the activity or stability of AFF1 protein.
Dysregulation or dysfunction of AFF1 protein can affect transcriptional regulation, perturb gene expression networks, and contribute to disease development.
The expression of AFF1 protein is regulated by specific factors and signaling pathways.
AFF1 protein plays a role in gene transcription or chromatin remodeling, and its function can be investigated using techniques like chromatin immunoprecipitation or gene expression analysis.
The subcellular localization of AFF1 protein can be experimentally determined using techniques such as immunofluorescence microscopy or subcellular fractionation.
AFF1 protein may interact with specific molecules or participate in protein complexes, which have functional implications in cellular processes.
Customer Reviews (3)
Write a reviewInvestigating protein-protein interactions in cellular senescence for aging-related diseases.
Mapping protein-protein interactions in immune checkpoint regulation for immunotherapy.
Unraveling protein-protein interactions in RNA splicing for gene expression regulation.
Ask a Question for All AFF1 Products
Required fields are marked with *
My Review for All AFF1 Products
Required fields are marked with *
Inquiry Basket