Recombinant Human AK4, His-tagged

• Cat.No.: AK4-27152TH
• Product Overview: Recombinant full length Human AK3L1 (amino acids 1-223) with N terminal His tag; 259 aa, 29.3 kDa.

Specification

• Description: This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1.
• Protein length: 223 amino acids
• Conjugation: HIS
• Molecular Weight: 29.300kDa inclusive of tags
• Source: E. coli
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: pH: 8.00Constituents:0.32% Tris HCl, 20% Glycerol, 0.03% DTT
• Storage: Store at -20°C (dessicate conditions).
• Sequences of amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMASK LLRAVILGPP GSGKGTVSQR IAQNFGLQHL SSGHFLRENIKASTEVGEMA KQYIEKSLLV PDHVITRLMM SELENRRGQH WLLDGFPRTL GQAEALDKIC EVDLVISLNI PFETLKDRLS RRWIHPPSGR VYNLDFNPPH VHGIDDVTGE PLVQQEDDKP EAVAARLRQY KDVAKPVIEL YKSRGVLHQF SGTETNKIWP YVYTLFSNKI TPIQSKEAY
• Sequence Similarities: Belongs to the adenylate kinase family.

Gene Information

• Gene Name: AK4 adenylate kinase 4 [ Homo sapiens ]
• Official Symbol: AK4
• Synonyms: AK4; adenylate kinase 4; adenylate kinase 3 , adenylate kinase 3 like 1 , AK3, AK3L1; adenylate kinase isoenzyme 4, mitochondrial
• Gene ID: 205
• mRNA Refseq: NM_001005353
• Protein Refseq: NP_001005353
• MIM: 103030
• Uniprot ID: P27144
• Chromosome Location: 1p31.3
• Pathway: Metabolic pathways, organism-specific biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem
• Function: ATP binding; GTP binding; adenylate kinase activity; nucleotide binding; transferase activity