Recombinant fragment of Human Alas1 with N terminal proprietary tag, 36.41kDa.
Delta-aminolevulinate synthase (ALAS; EC 22.214.171.124) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2 (MIM 301300).
98 amino acids
36.410kDa inclusive of tags
pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids:
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.