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Recombinant Human ANG

Cat.No.: ANG-27314TH
Product Overview: Recombinant full length Human Angiogenin with an N terminal proprietary tag; predicted mwt: 39.64 kDa inclusive of tag.
Description: The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5 exons. Each gene splices to a unique downstream exon that contains its complete coding region.
Protein length: 123 amino acids
Molecular Weight: 39.640kDa inclusive of tags
Source: Wheat germ
Tissue specificity: Expressed predominantly in the liver. Also detected in endothelial cells and spinal cord neurons.
Form: Liquid
Purity: Proprietary Purification
Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids: QDNSRYTHFLTQHYDAKPQGRDDRYCESIMRRRGLTSPCK DINTFIHGNKRSIKAICENKNGNPHRENLRISKSSFQVTT CKLHGGSPWPPCQYRATAGFRNVVVACENGLPVHLDQSIF RRP
Sequence Similarities: Belongs to the pancreatic ribonuclease family.
Gene Name: ANG angiogenin, ribonuclease, RNase A family, 5 [ Homo sapiens ]
Official Symbol: ANG
Synonyms: ANG; angiogenin, ribonuclease, RNase A family, 5; angiogenin; RNASE5;
Gene ID: 283
mRNA Refseq: NM_001097577
Protein Refseq: NP_001091046
MIM: 105850
Uniprot ID: P03950
Chromosome Location: 14q11.1-q11.2
Function: DNA binding; actin binding; copper ion binding; endonuclease activity; heparin binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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