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Home > Products > Antibody > Monoclonal Antibodies > Recombinant Human ANGPTL3, FLAG-tagged

Recombinant Human ANGPTL3, FLAG-tagged

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Cat.No.:
ANGPTL3-27351TH
Product Overview:
Recombinant fragment corresponding to amino acids 1-222 of Human ANGPTL3 with a C terminal DDDDK tag; MWt 25 kDa .
Description:
The protein encoded by this gene is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis.
Protein length:
222 amino acids
Conjugation:
FLAG
Molecular Weight:
25.000kDa inclusive of tags
Source:
HEK 293 cells
Tissue specificity:
Expressed principally in liver. Weakly expressed in kidney.
Form:
Liquid
Purity:
>90% by SDS-PAGE
Storage buffer:
Preservative: NoneConstituents: PBS
Storage:
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequence Similarities:
Contains 1 fibrinogen C-terminal domain.


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Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
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45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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