Recombinant Human ANGPTL3, FLAG-tagged
Cat.No. : | ANGPTL3-27353TH |
Product Overview : | Recombinant fragment corresponding to amino acids 224-460 of Human ANGPTL3 with an N terminal DDDDK tag; MWt 35 kDa by SDS PAGE. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis. |
Protein length : | 237 amino acids |
Conjugation : | FLAG |
Molecular Weight : | 35.000kDa inclusive of tags |
Source : | HEK 293 cells |
Tissue specificity : | Expressed principally in liver. Weakly expressed in kidney. |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: PBS |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Sequence Similarities : | Contains 1 fibrinogen C-terminal domain. |
Gene Name : | ANGPTL3 angiopoietin-like 3 [ Homo sapiens ] |
Official Symbol : | ANGPTL3 |
Synonyms : | ANGPTL3; angiopoietin-like 3; ANGPT5; angiopoietin-related protein 3; angiopoietin 5; |
Gene ID : | 27329 |
mRNA Refseq : | NM_014495 |
Protein Refseq : | NP_055310 |
MIM : | 604774 |
Uniprot ID : | Q9Y5C1 |
Chromosome Location : | 1p31.1-p22.3 |
Pathway : | Integrins in angiogenesis, organism-specific biosystem; |
Function : | cell surface binding; enzyme inhibitor activity; growth factor activity; integrin binding; phospholipase inhibitor activity; |
Products Types
◆ Recombinant Protein | ||
ANGPTL3-340H | Recombinant Human ANGPTL3 Protein, His (Fc)-Avi-tagged | +Inquiry |
ANGPTL3-117H | Recombinant Human ANGPTL3 Protein, His-tagged | +Inquiry |
Angptl3-174M | Active Recombinant Mouse Angptl3 Protein, N-HA-tagged | +Inquiry |
Angptl3-1626M | Recombinant Mouse Angptl3 Protein, Myc/DDK-tagged | +Inquiry |
ANGPTL3-485H | Recombinant Human ANGPTL3 Protein | +Inquiry |
◆ Lysates | ||
ANGPTL3-8862HCL | Recombinant Human ANGPTL3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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