"APOA5" Related Products

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Recombinant Human APOA5, Protein A-tagged

Cat.No.: APOA5-26876TH
Product Overview: Recombinant full-length Human Apolipoprotein A V with C-Terminal DDDDK tag.
Description: The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified.
Protein length: 343 amino acids
Conjugation: FLAG
Molecular Weight: 40.100kDa inclusive of tags
Source: HEK 293 cells
Tissue specificity: Liver and plasma.
Form: Lyophilised:Add deionized water (200 μl) to prepare a working stock solution of 0.5 mg/mL
Purity: by SDS-PAGE
Storage buffer: pH: 7.50Constituents:0.24% Tris, 0.29% Sodium chloride
Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids: RKGFWDYFSQ TSGDKGRVEQ IHQQKMAREP ATLKDSLEQD LNNMNKFLEK LRPLSGSEAP RLPQDPVGMR RQLQEELEEV KARLQPYMAE AHELVGWNLE GLRQQLKPYT MDLMEQVALR VQELQEQLRV VGEDTKAQLL GGVDEAWALL QGLQSRVVHH TGRFKELFHP YAESLVSGIG RHVQELHRSV APHAPASPAR LSRCVQVLSR KLTLKAKALH ARIQQNLDQL REELSRAFAG TGTEEGAGPD PQMLSEEVRQ RLQAFRQDTY LQIAAFTRAI DQETEEVQQQ LAPPPPGHSA FAPEFQQTDS GKVLSKLQAR LDDLWEDITH SLHDQGHSHL GDPAAADYKD DDDK
Sequence Similarities: Belongs to the apolipoprotein A1/A4/E family.
Gene Name: APOA5 apolipoprotein A-V [ Homo sapiens ]
Official Symbol: APOA5
Synonyms: APOA5; apolipoprotein A-V; APOA V; RAP3;
Gene ID: 116519
mRNA Refseq: NM_001166598
Protein Refseq: NP_001160070
MIM: 606368
Uniprot ID: Q6Q788
Chromosome Location: 11q23
Pathway: Chylomicron-mediated lipid transport, organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Lipid digestion, mobilization, and transport, organism-specific biosystem; Lipoprotein metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem;
Function: enzyme activator activity; enzyme binding; heparin binding; contributes_to heparin binding; lipase activator activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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