Native Human APOC2 protein

• Cat.No.: APOC2-27331TH
• Product Overview: Native Human APOC2 was purified from Human Plasma.

Specification

• Description: This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene.
• Source: Human Plasma
• Species: Human
• Form: Lyophilized from 32.1 ul 10 mM NH4HCO3, pH 7.4
• Molecular Mass: 8800 kDa
• Purity: >=95% by SDS-PAGE
• Notes: Prepared from fresh, non-frozen plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
• Storage: <= -20 centigrade or lower
• Reconstitution: After initial centrifugation, we suggest the re-addition of the lyophilization buffer (10 mM NH4HCO3, pH 7.4) to the original volume, followed by gentle swirling and/or vortexing to ensure adequate homogenization. If further dilution is required, please use the lyophilization buffer.

Gene Information

• Gene Name: APOC2 apolipoprotein C-II [ Homo sapiens ]
• Official Symbol: APOC2
• Synonyms: APOC2; apolipoprotein C-II; apolipoprotein C2; APO-CII; APOC-II; MGC75082
• Gene ID: 344
• mRNA Refseq: NM_000483
• Protein Refseq: NP_000474
• MIM: 608083
• UniProt ID: P02655