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Recombinant Human APOH, His-tagged

Cat.No.: APOH-26746TH
Product Overview: Recombinant full length human Apolipoprotein H produced in SF9 insect cells with a 6xHis tag; 326 amino acids, 45 kDa.
Description: Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies.APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.
Conjugation: HIS
Tissue specificity: Expressed by the liver and secreted in plasma.
Biological activity: APOH-26746TH is reactive with Goodpasture patient sera.
Form: Liquid
Purity: >90% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 200mM Sodium chloride, 16mM HEPES, pH 7.2
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities: Contains 4 Sushi (CCP/SCR) domains.
Gene Name: APOH apolipoprotein H (beta-2-glycoprotein I) [ Homo sapiens ]
Official Symbol: APOH
Synonyms: APOH; apolipoprotein H (beta-2-glycoprotein I); B2G1; beta-2-glycoprotein 1; beta 2 glycoprotein I; BG;
Gene ID: 350
mRNA Refseq: NM_000042
Protein Refseq: NP_000033
MIM: 138700
Uniprot ID: P02749
Chromosome Location: 17q23-qter
Function: eukaryotic cell surface binding; glycoprotein binding; heparin binding; lipid binding; lipoprotein lipase activator activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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