Recombinant Human Activating Transcription Factor 2, GST-tagged
Cat.No. : | ATF2-1432H |
Product Overview : | Recombinant human ATF2 (1-254) was expressed inE. colicells using a N-terminal GST tag. MW=55kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | ATF2-1432H |
Description : | Activating transcription factor (ATF)-2, also designated CRE-BP1, is a member of the ATF/cyclic AMP-responsive element binding protein family of transcription factors. ATF2 has two unique characteristics: it mediates the adenovirus E1A-induced trans-activation and forms a heterodimer with c-Jun. ATF2 is a target of the JNK signal transduction pathway. ATF2 is phosphorylated by JNK on two closely spaced threonine residues within the NH2-terminal activation domain. The replacement of these phosphorylation sites with alanine inhibited the transcriptional activity of ATF2. Furthermore, p38 MAPK can also phosphorylate ATF2. |
Source : | E. coli. |
Sequence : | Full-length. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | ATF2 activating transcription factor 2 [ Homo sapiens ] |
Synonyms : | ATF2; activating transcription factor 2; HB16; CREB2; TREB7; CRE-BP1; MGC111558; cAMP responsive element binding protein 2; clic AMP-dependent transcription factor ATF-2; cAMP-dependent transcription factor ATF-2; cAMP-dependent transcription factor ATF-2; cAMP response element-binding protein CRE-BP1; Cyclic AMP-responsive element-binding protein 2; CREB-2 |
Gene ID : | 1386 |
mRNA Refseq : | NM_001880 |
Protein Refseq : | NP_001871 |
UniProt ID : | P15336 |
Chromosome Location : | 2q32 |
MIM : | 123811 |
Pathway : | MAPK signaling pathway; Signaling in Immune system |
Function : | RNA polymerase II transcription factor activity; metal ion binding; protein dimerization activity; sequence-specific DNA binding; transcription coactivator activity; transcription factor activity; zinc ion binding |
Products Types
◆ Recombinant Protein | ||
ATF2-2659H | Recombinant Human ATF2 protein(351-440 aa), C-His-tagged | +Inquiry |
ATF2-6867H | Recombinant Human ATF2 protein(Met1-Ser505), His&GST-tagged | +Inquiry |
ATF2-494R | Recombinant Rat ATF2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ATF2-8502H | Recombinant Huamn ATF2, His-tagged | +Inquiry |
ATF2-26187TH | Recombinant Human ATF2 | +Inquiry |
◆ Lysates | ||
ATF2-518HCL | Recombinant Human ATF2 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0111 | ATF2 (pT69/pT71) Transcription Factor Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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