Recombinant Human ATF2
Cat.No. : | ATF2-27044TH |
Product Overview : | Recombinant fragment with N-terminal tag, corresponding to N terminal amino acids 1-254 of Human ATF2 |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined. |
Source : | E. coli |
Tissue specificity : | Abundant expression seen in the brain. |
Form : | Liquid |
Storage buffer : | Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7.5 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MSDDKPFLCT APGCGQRFTN EDHLAVHKHK HEMTLKFGPA RNDSVIVADQ TPTPTRFLKN CEEVGLFNEL ASPFENEFKK ASEDDIKKMP LDLSPLATPI IRSKIEEPSV VETTHQDSPL PHPESTTSDE KEVPLAQTAQ PTSAIVRPAS LQVPNVLLTS SDSSVIIQQA VPSPTSSTVI TQAPSSNRPI VPVPGPFPLL LHLPNGQTMP VAIPASITSS NVHVPAAVPL VRPVTMVPSV PGIPGPSSPQ PVQS |
Sequence Similarities : | Belongs to the bZIP family. ATF subfamily.Contains 1 bZIP domain.Contains 1 C2H2-type zinc finger. |
Gene Name : | ATF2 activating transcription factor 2 [ Homo sapiens ] |
Official Symbol : | ATF2 |
Synonyms : | ATF2; activating transcription factor 2; cAMP responsive element binding protein 2 , CREB2; cyclic AMP-dependent transcription factor ATF-2; CRE BP1; HB16; TREB7; |
Gene ID : | 1386 |
mRNA Refseq : | NM_001880 |
Protein Refseq : | NP_001871 |
MIM : | 123811 |
Uniprot ID : | P15336 |
Chromosome Location : | 2q32 |
Pathway : | ATF-2 transcription factor network, organism-specific biosystem; Activated TLR4 signalling, organism-specific biosystem; Activation of the AP-1 family of transcription factors, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; |
Function : | DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; chromatin binding; metal ion binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
ATF2-6867H | Recombinant Human ATF2 protein(Met1-Ser505), His&GST-tagged | +Inquiry |
ATF2-2659H | Recombinant Human ATF2 protein(351-440 aa), C-His-tagged | +Inquiry |
ATF2-494R | Recombinant Rat ATF2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ATF2-26187TH | Recombinant Human ATF2 | +Inquiry |
ATF2-6466C | Recombinant Chicken ATF2 | +Inquiry |
◆ Lysates | ||
ATF2-518HCL | Recombinant Human ATF2 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0111 | ATF2 (pT69/pT71) Transcription Factor Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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