Recombinant Human BTC

• Cat.No.: BTC-26709TH
• Product Overview: Recombinant Betacellulin fragment (Human), 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein.

Specification

• Description: The protein encoded by this gene is a member of the EGF family of growth factors. It is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor.
• Source: E. coli
• Tissue specificity: Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine.
• Form: Lyophilised
• Purity: >95% by SDS-PAGE
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Sequences of amino acids: DGNSTRSPET NGLLCGDPEE NCAATTTQSK RKGHFSRCPK QYKHYCIKGR CRFVVAEQTP SCVCDEGYIG ARCERVDLFY
• Sequence Similarities: Contains 1 EGF-like domain.

Gene Information

• Gene Name: BTC betacellulin [ Homo sapiens ]
• Official Symbol: BTC
• Synonyms: BTC; betacellulin; probetacellulin
• Gene ID: 685
• mRNA Refseq: NM_001729
• Protein Refseq: NP_001720
• MIM: 600345
• Uniprot ID: P35070
• Chromosome Location: 4q13-q21
• Pathway: ErbB receptor signaling network, organism-specific biosystem; ErbB signaling pathway, organism-specific biosystem; ErbB signaling pathway, organism-specific biosystem; ErbB signaling pathway, conserved biosystem; ErbB4 signaling events, organism-specific biosystem
• Function: epidermal growth factor receptor binding; growth factor activity