Recombinant Human CA1, His-tagged

Cat.No.

CA1-27387TH

Product Overview

Recombinant full length Human Carbonic Anhydrase I with a N terminal His tag. 281 amino acids with a predicted MWt 31 kDa including tag.

Description

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Variants of this gene have been described in some populations. Multiple alternatively spliced variants, encoding the same protein, have been identified. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature.

Protein length

261 amino acids

Conjugation

HIS

Molecular Weight

31.000kDa inclusive of tags

Source

E. coli

Form

Liquid

Purity

>95% by SDS-PAGE

Storage buffer

pH: 8.00Constituents:0.32% Tris HCl, 0.02% DTT, 10% Glycerol

Storage

Please see Notes section

Sequences of amino acids

MGSSHHHHHH SSGLVPRGSH MASPDWGYDD KNGPEQWSKL YPIANGNNQS PVDIKTSETK HDTSLKPISV SYNPATAKEI INVGHSFHVN FEDNDNRSVL KGGPFSDSYR LFQFHFHWG
S TNEHGSEHTV DGVKYSAELH VAHWNSAKYS SLAEAASKAD GLAVIGVLMK VGEANPKLQK VLDALQAIKT KGKRAPFTNF DPSTLLPSSL DFWTYPGSLT HPPLYESVTW IICKESI
SVS SEQLAQFRSL LSNVEGDNAV PMQHNNRPTQ PLKGRTVRAS F

Sequence Similarities

Belongs to the alpha-carbonic anhydrase family.

Antigen Gene Information