Recombinant Human CAPN1, His-tagged
Cat.No. : | CAPN1-27399TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 214-500 of Human Calpain 1 with N terminal His tag; 287 amino acids, 33kDa. |
- Specification
- Gene Information
- Related Products
Description : | The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. |
Conjugation : | HIS |
Source : | E. coli |
Tissue specificity : | Ubiquitous. |
Form : | Lyophilised:Reconstitute with 121 μl distilled water. |
Storage buffer : | Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | FEDFTGGVTEWYELRKAPSDLYQII LKALERGSLLGCSID ISSVLDMEAITFKKLVKGHAYSVTG AKQVNYRGQVVSL IRMRNPWGEVEWTGAWSDSSSEWNN VDPYERDQLRVKMEDGEFWMSFRDF MREFTRLEICNLTPDALKSRTIRKW NTT LYEGTWRRGSTAGGCRNYPATFWVN PQFKIRLDETDDP DDYGDRESGCSFVLALMQKHRRRER RFGRDMETIGFAVYE VPPELVGQPAVHLKRDFFLANASRA RSEQFINLREVST RFRLPPGEYVVVPST |
Sequence Similarities : | Belongs to the peptidase C2 family.Contains 1 calpain catalytic domain.Contains 4 EF-hand domains. |
Gene Name : | CAPN1 calpain 1, (mu/I) large subunit [ Homo sapiens ] |
Official Symbol : | CAPN1 |
Synonyms : | CAPN1; calpain 1, (mu/I) large subunit; calpain-1 catalytic subunit; CANP; CANPL1; muCANP; muCL; |
Gene ID : | 823 |
mRNA Refseq : | NM_001198868 |
Protein Refseq : | NP_001185797 |
MIM : | 114220 |
Uniprot ID : | P07384 |
Chromosome Location : | 11q13 |
Pathway : | Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Focal Adhesion, organism-specific biosystem; |
Function : | calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; peptidase activity; |
Products Types
◆ Recombinant Protein | ||
CAPN1-452R | Recombinant Rhesus Macaque CAPN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CAPN1-1213M | Recombinant Mouse CAPN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CAPN1-0355H | Recombinant Human CAPN1 Protein, GST-Tagged | +Inquiry |
CAPN1-2587H | Recombinant Human CAPN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CAPN1-782R | Recombinant Rat CAPN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
CAPN1-8448H | Active Native Human CAPN1 | +Inquiry |
CAPN1-186p | Active Native porcine Calpain-1 | +Inquiry |
CAPN1-65P | Active Native Porcine Porcine Calpain 1 | +Inquiry |
◆ Lysates | ||
CAPN1-7865HCL | Recombinant Human CAPN1 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-0151 | CAPN1 Inhibitor (Human) Screening Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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