Recombinant Human NFATC1, GST-tagged
| Cat.No. : |
NFATC-1474H |
| Product Overview : |
Recombinant full-length human NFATC1 was expressed by baculovirus inSf9insect cells using an N-terminal GST tag. MW = 125 kDa. |
- Specification
- Gene Information
- Related Products
| Cat. No. : |
NFATC-1474H |
| Description : |
NFATC1 is a member of the NFAT family of proteins which are Ca2+/calcineurin-responsive transcription factors primarily recognized for their central roles in T lymphocyte activation and cardiac valve development. NFAT consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T-cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to the NFAT family of transcription factors play a central role in inducible gene transcription during immune response. The product of NFATC1 is an inducible nuclear component and functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. |
| Source : |
Sf9 insect cells using baculovirus. |
| Sequence : |
Full-length. |
| Applications : |
Western Blot. |
| Storage And Stability : |
Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
| Gene Name : |
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 [ Homo sapiens ] |
| Synonyms : |
NFATC1; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1; NFAT2; NFATc; NF-ATC; MGC138448; NFAT transcription complex cytosolic component; Nuclear factor of activated T-cells, cytoplasmic 1; NF-ATc1; NFATC; NFAT transcription complex cytosolic component |
| Gene ID : |
4772 |
| mRNA Refseq : |
NM_006162 |
| Protein Refseq : |
NP_006153 |
| MIM : |
600489 |
| UniProt ID : |
O95644 |
| Chromosome Location : |
18q23 |
| Pathway : |
Axon guidance; B cell receptor signaling pathway; Natural killer cell mediated cytotoxicity; T cell receptor signaling pathway; VEGF signaling pathway; Wnt signaling pathway |
| Function : |
FK506 binding; promoter binding; protein binding; transcription activator activity; transcription factor activity |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
