Recombinant Human CD1B
Cat.No. : | CD1B-27106TH |
Product Overview : | Recombinant fragment of Human CD1b (amino acids 19-110) with N terminal proprietary tag, 35.75kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. |
Protein length : | 92 amino acids |
Molecular Weight : | 35.750kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | EHAFQGPTSFHVIQTSSFTNSTWAQ TQGSGWLDDLQIHGWDSDSGTAIFL KPWSKGNFSDKEVAELEEIFRVYIF GFAREVQDFAGDFQMKY |
Sequence Similarities : | Contains 1 Ig-like (immunoglobulin-like) domain. |
Gene Name : | CD1B CD1b molecule [ Homo sapiens ] |
Official Symbol : | CD1B |
Synonyms : | CD1B; CD1b molecule; CD1, CD1b antigen , CD1B antigen, b polypeptide; T-cell surface glycoprotein CD1b; |
Gene ID : | 910 |
mRNA Refseq : | NM_001764 |
Protein Refseq : | NP_001755 |
MIM : | 188360 |
Uniprot ID : | P29016 |
Chromosome Location : | 1q22-q23 |
Pathway : | Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; |
Function : | protein binding; |
Products Types
◆ Recombinant Protein | ||
CD1B-164H | Recombinant Human CD1B Protein, C-His-tagged | +Inquiry |
CD1B-317R | Recombinant Rhesus CD1B Protein, His-tagged | +Inquiry |
CD1B-548R | Recombinant Rhesus Macaque CD1B Protein, His (Fc)-Avi-tagged | +Inquiry |
CD1B-7331H | Recombinant Human CD1B protein(Met1-Ser303), hFc-tagged | +Inquiry |
CD1B-3039H | Recombinant Human CD1B Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
CD1B-1504HCL | Recombinant Human CD1B cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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