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Recombinant Human CD80, Fc-tagged

Cat.No. : CD80-27510TH
Product Overview : Recombinant human CD80-Fc fusion protein containing the extracellular domain of human CD80 fused to Human Fc.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.
Conjugation : Fc
Tissue specificity : Expressed on activated B-cells, macrophages and dendritic cells.
Form : Liquid
Purity : Protein A purified
Storage buffer : Preservative: NoneConstituents: PBS, pH 7.2
Storage : Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MGHTRRQGTSPSKCPYLNFFQLLVLAGLSHFCSGVIHVTK EVKEVATLSCGHNVSVEELAQTRIYWQKEKKMVLTMMSGD MNIWPEYKNRTIFDITNNLSIVILALRPSDEGTYECVVLK YEKDAFKREHLAEVTLSVKADFPTPSISDFEIPTSNIRRI ICSTSGGFPEPHLSWLENGEELNAINTTVSQDPETELYAV SSKLDFNMTTNHSFMCLIKYGHLRVNQTFNWNTTKQEHFP DDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEV TCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNST YRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKA KGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAV EWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQ GNVFSCSVMHEALHNHYTQKSLSLSPGKExtracel lular domain (amino acids 1-241) of human B7.1 sequence is underlined.Human Fc sequence is in italics.
Sequence Similarities : Contains 1 Ig-like C2-type (immunoglobulin-like) domain.Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Gene Name : CD80 CD80 molecule [ Homo sapiens ]
Official Symbol : CD80
Synonyms : CD80; CD80 molecule; CD28LG, CD28LG1, CD80 antigen (CD28 antigen ligand 1, B7 1 antigen) , CD80 molecule; T-lymphocyte activation antigen CD80; B lymphocyte activation antigen B7; B7 1; B7.1;
Gene ID : 941
mRNA Refseq : NM_005191
Protein Refseq : NP_005182
MIM : 112203
Uniprot ID : P33681
Chromosome Location : 3q13.3-q21
Pathway : Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem;
Function : coreceptor activity; protein binding; receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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