Recombinant Human CDA, His-tagged
Cat.No. : | CDA-26955TH |
Product Overview : | Recombinant full length Human CDA with an N terminal His tag; 166aa, 18.3kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias. |
Protein length : | 146 amino acids |
Conjugation : | HIS |
Molecular Weight : | 18.300kDa inclusive of tags |
Source : | E. coli |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 40% Glycerol, 20mM Tris HCl, 2mM EDTA, 100mM Sodium chloride, 1mM DTT, pH 8.0 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MGSSHHHHHHSSGLVPRGSHMAQKR PACTLKPECVQQLLVCSQEAKQSAY CPYSHFPVGAALLTQEGRIFKGCNI ENACYPLGICAERTAIQKAVSEGYK DFRAIAIASDMQDDFISPCGACRQV MREFGTNWPVYMTKPDGTYIVMTVQ ELLPSSFGPEDLQKTQ |
Gene Name : | CDA cytidine deaminase [ Homo sapiens ] |
Official Symbol : | CDA |
Synonyms : | CDA; cytidine deaminase; CDD; |
Gene ID : | 978 |
mRNA Refseq : | NM_001785 |
Protein Refseq : | NP_001776 |
MIM : | 123920 |
Uniprot ID : | P32320 |
Chromosome Location : | 1p36.2-p35 |
Pathway : | Drug metabolism - other enzymes, organism-specific biosystem; Drug metabolism - other enzymes, conserved biosystem; Fluoropyrimidine Activity, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; |
Function : | cytidine deaminase activity; cytidine deaminase activity; hydrolase activity; metal ion binding; nucleoside binding; |
Products Types
◆ Recombinant Protein | ||
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CDA-598H | Recombinant Human CDA Protein, His-tagged | +Inquiry |
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CDA-796H | Recombinant Human Cytidine Deaminase, His-tagged | +Inquiry |
CDA-317HCL | Recombinant Human CDA Over-ex<x>pression Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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