Recombinant Human CDC25C
Cat.No. : | CDC25C-27900TH |
Product Overview : | Recombinant full length Human Cdc25C with N-terminal proprietary tag, 84kDa. |
- Specification
- Gene Information
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Description : | This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. |
Protein length : | 473 amino acids |
Molecular Weight : | 84.000kDa inclusive of tags |
Source : | Baculovirus infected sf9 cells |
Biological activity : | The Specific activity of CDC25C-27900TH was determined to be 22 nmol/min/mg. |
Form : | Liquid |
Purity : | by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the MPI phosphatase family.Contains 1 rhodanese domain. |
Gene Name : | CDC25C cell division cycle 25 homolog C (S. pombe) [ Homo sapiens ] |
Official Symbol : | CDC25C |
Synonyms : | CDC25C; cell division cycle 25 homolog C (S. pombe); CDC25, cell division cycle 25 homolog C (S. cerevisiae) , cell division cycle 25C; M-phase inducer phosphatase 3; PPP1R60; protein phosphatase 1; regulatory subunit 60; |
Gene ID : | 995 |
mRNA Refseq : | NM_001790 |
Protein Refseq : | NP_001781 |
MIM : | 157680 |
Uniprot ID : | P30307 |
Chromosome Location : | 5q31 |
Pathway : | Activation of ATR in response to replication stress, organism-specific biosystem; Cell Cycle Checkpoints, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem; |
Function : | WW domain binding; hydrolase activity; protein binding; protein tyrosine phosphatase activity; |
Products Types
◆ Recombinant Protein | ||
CDC25C-0918H | Recombinant Human CDC25C Protein, GST-Tagged | +Inquiry |
Cdc25c-853M | Recombinant Mouse Cdc25c Protein, MYC/DDK-tagged | +Inquiry |
CDC25C-1480M | Recombinant Mouse CDC25C Protein, His (Fc)-Avi-tagged | +Inquiry |
CDC25C-11001H | Recombinant Human CDC25C, His-tagged | +Inquiry |
CDC25C-699H | Recombinant Human Cell Division Cycle 25 Homolog C (S. Pombe) | +Inquiry |
◆ Lysates | ||
CDC25C-7664HCL | Recombinant Human CDC25C 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Ask a questionCustomer Reviews (3)
Write a reviewFast and timely shipment helped me to get satisfactory experimental results in short time.
The staff was very nice, communicated with me positively and solved a lot of technical problems.
The technician gave me a thorough introduction to the CDC25C protein so that I could understand its biochemical properties.
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