Recombinant Human CDC37, His-tagged
Cat.No. : | CDC37-26222TH |
Product Overview : | Recombinant full length Human Cdc37 with an N terminal His tag; 388 amino acids with tag, Predicted MWt 45.71 kDa. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. |
Protein length : | 378 amino acids |
Conjugation : | HIS |
Molecular Weight : | 45.710kDa inclusive of tags |
Source : | E. coli |
Form : | Lyophilised:Add deionized water to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the ce |
Storage buffer : | Preservative: NoneConstituents: 50mM Sodium chloride, 20mM Tris, pH 7.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MKHHHHHHASMVDYSVWDHIEVSDD EDETHPNIDTASLFRWRHQARVERM EQFQKEKEELDRGCRECKRKVAECQ RKLKELEVAEGGKAELERLQAEAQQ LRKEERSWEQKLEEMRKKEKSMPWN VDTLSKDGFSKSMVNTKPEKTEEDS EEVREQKHKTFVEKYEKQIKHFGML RRWDDSQKYLSDNVHLVCEETANYL VIWCIDLEVEEKCALMEQVAHQTIV MQFILELAKSLKVDPRACFRQFFTK IKTADRQYMEGFNDELEAFKERVRG RAKLRIEKAMKEYEEEERKKRLGPG GLDPVEVYESLPEELQKCFDVKDVQ MLQDAISKMDPTDAKYHMQRCIDSG LWVPNSKASEAKEGEEAGPGDPLLE AVPKTGDEKDVSV |
Sequence Similarities : | Belongs to the CDC37 family. |
Gene Name : | CDC37 cell division cycle 37 homolog (S. cerevisiae) [ Homo sapiens ] |
Official Symbol : | CDC37 |
Synonyms : | CDC37; cell division cycle 37 homolog (S. cerevisiae); CDC37 (cell division cycle 37, S. cerevisiae, homolog) , CDC37 cell division cycle 37 homolog (S. cerevisiae); hsp90 co-chaperone Cdc37; CDC37 (cell division cycle 37; S. cerevisiae; homolog); CDC37 |
Gene ID : | 11140 |
mRNA Refseq : | NM_007065 |
Protein Refseq : | NP_008996 |
MIM : | 605065 |
Uniprot ID : | Q16543 |
Chromosome Location : | 19p13.2 |
Pathway : | Androgen Receptor Signaling Pathway, organism-specific biosystem; LKB1 signaling events, organism-specific biosystem; TNF-alpha/NF-kB Signaling Pathway, organism-specific biosystem; |
Function : | Hsp90 protein binding; heat shock protein binding; protein binding; unfolded protein binding; |
Products Types
◆ Recombinant Protein | ||
CDC37-3072H | Recombinant Human CDC37 protein(Met1-Val378), GST-tagged | +Inquiry |
CDC37-555H | Recombinant Human CDC37 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDC37-0930H | Recombinant Human CDC37 Protein, GST-Tagged | +Inquiry |
CDC37-933R | Recombinant Rat CDC37 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDC37-3124H | Recombinant Human CDC37 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
CDC37-001MCL | Recombinant Mouse CDC37 cell lysate | +Inquiry |
CDC37-648HCL | Recombinant Human CDC37 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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