Active Recombinant Human CDK9/CCNK protein, GST-tagged
| Cat.No. : | CDK9-26809TH |
| Product Overview : | Recombinant full-length human CDK9 and CCNK were co-expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag on both proteins. |
- Specification
- Gene Information
- Related Products
| Description : | CDK9/CCNK is a member of the cyclin-dependent protein kinase (CDK) family. CDK9 is closely related to cdc28 and cdc2 and is an important regulator of the cell cycle. CDK9 is a component of the multiprotein complex TAK/P-TEFβ. CDK9 can modulate RNA polymerase II-directed transcription by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. CDK9 forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. CDK9 also interacts with the HIV-1 Tat protein which suggested a possible involvement of this protein in AIDS. |
| Source : | Insect cell |
| Species : | Human |
| Tag : | GST |
| Form : | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Bio-activity : | 18nmol/min/mg |
| Molecular Mass : | CDK9~68 kDa; CCNK~67 kDa |
| Purity : | The purity of CDK9/CCNK was determined to be >85% by densitometry. |
| Applications : | Kinase Assay; WB |
| Stability : | 1 year at -70 centigrade |
| Storage : | Store product at -70 centigrade |
| Concentration : | 0.1 μg/μL |
| Gene Name : | cyclin dependent kinase 9 [ Homo sapiens (human) ] |
| Official Symbol : | CDK9 |
| Synonyms : | TAK; C-2k; CTK1; CDC2L4; PITALRE; CPR4 |
| Gene ID : | 1025 |
| mRNA Refseq : | NM_001261 |
| Protein Refseq : | NP_001252 |
| MIM : | 603251 |
| UniProt ID : | P50750 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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