Recombinant Human CHRNA1
Cat.No. : | CHRNA1-30388TH |
Product Overview : | Recombinant fragment of Human Nicotinic Acetylcholine Receptor alpha 1 with N terminal proprietary tag, 35.09kDa. |
- Specification
- Gene Information
- Related Products
Description : | The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha isoforms and 1 each of beta, gamma, and delta subunits.2 This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Protein length : | 86 amino acids |
Molecular Weight : | 35.090kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Isoform 1 is only expressed in skeletal muscle. Isoform 2 is constitutively expressed in skeletal muscle, brain, heart, kidney, liver, lung and thymus. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | SYCEIIVTHFPFDEQNCSMKLGTWT YDGSVVAINPESDQPDLSNFMESGE WVIKESRGWKHSVTYSCCPDTPYLD ITYHFVMQRLP |
Sequence Similarities : | Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-1/CHRNA1 sub-subfamily. |
Gene Name : | CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) [ Homo sapiens ] |
Official Symbol : | CHRNA1 |
Synonyms : | CHRNA1; cholinergic receptor, nicotinic, alpha 1 (muscle); cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) , CHRNA; acetylcholine receptor subunit alpha; |
Gene ID : | 1134 |
mRNA Refseq : | NM_000079 |
Protein Refseq : | NP_000070 |
MIM : | 100690 |
Uniprot ID : | P02708 |
Chromosome Location : | 2q24-q32 |
Pathway : | Acetylcholine Binding And Downstream Events, organism-specific biosystem; Activation of Nicotinic Acetylcholine Receptors, organism-specific biosystem; Effects of Botulinum toxin, organism-specific biosystem; ErbB2/ErbB3 signaling events, organism-specific biosystem; Highly calcium permeable nicotinic acetylcholine receptors, organism-specific biosystem; |
Function : | contributes_to acetylcholine binding; contributes_to acetylcholine receptor activity; acetylcholine-activated cation-selective channel activity; contributes_to acetylcholine-activated cation-selective channel activity; extracellular ligand-gated ion chann; |
Products Types
◆ Recombinant Protein | ||
CHRNA1-1662M | Recombinant Mouse CHRNA1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CHRNA1-406M | Recombinant Mouse CHRNA1 Protein (21-230 aa), His-SUMO-tagged | +Inquiry |
CHRNA1-407T | Recombinant Torpedo Californica CHRNA1 Protein (25-234 aa), His-SUMO-tagged | +Inquiry |
Chrna1-778R | Recombinant Rat Chrna1 Protein, His-tagged | +Inquiry |
CHRNA1-2696T | Recombinant Tetronarce Californica CHRNA1 Protein (25-234 aa), His-sumostar-tagged | +Inquiry |
◆ Lysates | ||
CHRNA1-7517HCL | Recombinant Human CHRNA1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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