Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human CHUK

Cat.No. : CHUK-27562TH
Product Overview : Recombinant full length Human IKK alpha with a N terminal proprietary tag; molecular weight 114 kDa including tag.
Unit
Price
Qty
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
Protein length : 745 amino acids
Molecular Weight : 114.000kDa inclusive of tags
Source : Baculovirus infected sf9 cells
Tissue specificity : Widely expressed.
Biological activity : Specific activity is 2.5nm/min/mg
Form : Liquid
Purity : Densitometry
Storage buffer : Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.Contains 1 protein kinase domain.
Publication :
Quantitation of the Dynamic Profiles of the Innate Immune Response Using Multiplex Selected Reaction Monitoring–Mass Spectrometry (2013)
Gene Name : CHUK conserved helix-loop-helix ubiquitous kinase [ Homo sapiens ]
Official Symbol : CHUK
Synonyms : CHUK; conserved helix-loop-helix ubiquitous kinase; TCF16; inhibitor of nuclear factor kappa-B kinase subunit alpha; IkBKA; IKK alpha; IKK1; IKKA; NFKBIKA;
Gene ID : 1147
mRNA Refseq : NM_001278
Protein Refseq : NP_001269
MIM : 600664
Uniprot ID : O15111
Chromosome Location : 10q24-q25
Pathway : AKT phosphorylates targets in the cytosol, organism-specific biosystem; Activated TLR4 signalling, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Adaptive Immune System, organism-specific biosystem;
Function : ATP binding; IkappaB kinase activity; nucleotide binding; protein binding; protein kinase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All CHUK Products

Required fields are marked with *

My Review for All CHUK Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends