Recombinant Human CLDN4
Cat.No. : | CLDN4-26708TH |
Product Overview : | Recombinant fragment of Human Claudin 4 (amino acids 29-78) with proprietary tag, 31.13kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an integral membrane protein, which belongs to the claudin family. The protein is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. |
Protein length : | 50 amino acids |
Molecular Weight : | 31.130kDa inclusive of tags |
Source : | Wheat germ |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.31% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MWRVTAFIGSNIVTSQTIWEGLWMN CVVQSTGQMQCKVYDSLLALPQDLQ |
Sequence Similarities : | Belongs to the claudin family. |
Gene Name : | CLDN4 claudin 4 [ Homo sapiens ] |
Official Symbol : | CLDN4 |
Synonyms : | CLDN4; claudin 4; CPETR, CPETR1; claudin-4; Clostridium perfringens enterotoxin receptor 1; CPE R; hCPE R; WBSCR8; Williams Beuren syndrome chromosomal region 8 protein; |
Gene ID : | 1364 |
mRNA Refseq : | NM_001305 |
Protein Refseq : | NP_001296 |
MIM : | 602909 |
Uniprot ID : | O14493 |
Chromosome Location : | 7q11.23 |
Pathway : | Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cell junction organization, organism-specific biosystem; Cell-Cell communication, organism-specific biosystem; Cell-cell junction organization, organism-specific biosystem; |
Function : | identical protein binding; structural molecule activity; transmembrane signaling receptor activity; |
Products Types
◆ Recombinant Protein | ||
Cldn4-901M | Recombinant Mouse Cldn4 Protein, MYC/DDK-tagged | +Inquiry |
CLDN4-612H | Recombinant Human CLDN4 Protein, His (Fc)-Avi-tagged | +Inquiry |
CLDN4-1443H | Recombinant Human CLDN4 Protein, GST-tagged | +Inquiry |
CLDN4-1733M | Recombinant Mouse CLDN4 Protein, His (Fc)-Avi-tagged | +Inquiry |
CLDN4-722R | Recombinant Rhesus Macaque CLDN4 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CLDN4-7462HCL | Recombinant Human CLDN4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionInhibiting CLDN4 function could enhance the efficacy of existing cancer therapies and potentially lead to the development of new treatment strategies.
CLDN4 is involved in regulating the entry of certain pathogens into host cells, making it a potential target for the development of antiviral and antibacterial therapies.
Research is underway to explore the potential of targeting CLDN4 to modulate tissue barrier function and alleviate the symptoms of autoimmune diseases.
Monitoring CLDN4 levels and function may provide valuable insights into the progression of IBD and help in the development of targeted therapies.
CLDN4 is also being studied in the context of kidney disease, skin disorders, and neurodegenerative diseases due to its role in maintaining tissue barrier function.
Customer Reviews (3)
Write a reviewThe CLDN4 protein showcases outstanding quality, ensuring its suitability for addressing my experimental requirements effectively.
the manufacturer's dedication to excellent technical support assures me that any challenges or obstacles I encounter will be swiftly resolved.
Its top-notch purity and integrity instill confidence in obtaining precise and reliable data, thereby enabling significant advancements in my research.
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