Recombinant Human CLDN7
Cat.No. : | CLDN7-27069TH |
Product Overview : | Recombinant fragment of Human Claudin 7 (amino acids 31-81) with proprietary tag, predicted MW 31.24kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found. |
Protein length : | 51 amino acids |
Molecular Weight : | 31.240kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Expressed in kidney, lung and prostate. Isoform 1 seems to be predominant, except in some normal prostate samples, where isoform 2 is the major form. Down-regulated in breast cancers, including ductal carcinoma in situ (DCIS), lobular carcinoma in situ (L |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.31% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | QMSSYAGDNIITAQAMYKGLWMDCV TQSTGMMSCKMYDSVLALSAALQAT R |
Sequence Similarities : | Belongs to the claudin family. |
Gene Name : | CLDN7 claudin 7 [ Homo sapiens ] |
Official Symbol : | CLDN7 |
Synonyms : | CLDN7; claudin 7; CEPTRL2, CPETRL2; claudin-7; Hs.84359; |
Gene ID : | 1366 |
mRNA Refseq : | NM_001185022 |
Protein Refseq : | NP_001171951 |
MIM : | 609131 |
Uniprot ID : | O95471 |
Chromosome Location : | 17 |
Pathway : | Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cell junction organization, organism-specific biosystem; Cell-Cell communication, organism-specific biosystem; Cell-cell junction organization, organism-specific biosystem; |
Function : | identical protein binding; protein binding; structural molecule activity; |
Products Types
◆ Recombinant Protein | ||
CLDN7-1446H | Recombinant Human CLDN7 Protein, GST-tagged | +Inquiry |
CLDN7-1735M | Recombinant Mouse CLDN7 Protein, His (Fc)-Avi-tagged | +Inquiry |
CLDN7-11299H | Recombinant Human CLDN7, GST-tagged | +Inquiry |
CLDN7-3541M | Recombinant Mouse CLDN7 Protein | +Inquiry |
◆ Lysates | ||
CLDN7-7459HCL | Recombinant Human CLDN7 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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