Recombinant Human CNTF
| Cat.No. : | CNTF-26841TH |
| Product Overview : | Recombinant full length protein (Human) |
- Specification
- Gene Information
- Related Products
| Description : | The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. |
| Source : | E. coli |
| Tissue specificity : | Nervous system. |
| Form : | Lyophilised:Reconstitute in 5mM Sodium phosphate pH 7.5 to a concentration of 0.1-1 mg/ml |
| Purity : | >95% by SDS-PAGE |
| Storage buffer : | Preservative: NoneConstituents: 5mM Sodium chloride, 5mM Sodium phosphate, pH 7.5 |
| Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
| Sequence Similarities : | Belongs to the CNTF family. |
| Gene Name : | CNTF ciliary neurotrophic factor [ Homo sapiens ] |
| Official Symbol : | CNTF |
| Synonyms : | CNTF; ciliary neurotrophic factor; HCNTF; |
| Gene ID : | 1270 |
| mRNA Refseq : | NM_000614 |
| Protein Refseq : | NP_000605 |
| MIM : | 118945 |
| Uniprot ID : | P26441 |
| Chromosome Location : | 11q12 |
| Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem; |
| Function : | ciliary neurotrophic factor receptor binding; cytokine activity; growth factor activity; interleukin-6 receptor binding; |
Products Types
| ◆ Native Protein | ||
| CNTF-26839TH | Native Human CNTF | +Inquiry |
| ◆ Lysates | ||
| CNTF-376HCL | Recombinant Human CNTF cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket
